[Transcript] – Are Your Expensive Multivitamins Even Absorbed…Or Are There Better Ways To Deliver Precious Nutrients To Your Body?

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Podcast from:  https://bengreenfieldfitness.com/podcast/supplements-podcasts/are-supplements-absorbed/

[00:00] Introduction

[02:48] What is a Biohacker

[11:29] Liposomal Delivery

[16:26] Nebulization

[19:43] Vaporization

[25:28] Sublinguals

[28:30] Transdermals

[31:04] Detoxing

[41:21] Simpleology

[46:01] End of Podcast

Ben:  Hey folks, it’s Ben Greenfield and if you’ve been listening to this podcast for any amount of time, then you know that we’ve talked about the concept of biohacking before.  And frankly, it seems like it’s a pretty sexy topic that gets thrown around the internet quite a bit and it’s a term that gets thrown around quite a bit.  Well, today, we’re going to dig in to the nitty-gritties of biohacking and kind of take a deep-dive into the rabbit hole of, especially, supplements and mind enhancing and detoxing and the utilization of biohacking for achieving some of those goals.  We’re going to have some fun on this one and I have a really cool guy on the call, he’s an author.  He’s an inventor.  He’s a serial entrepreneur and currently, his role is as the founder and the CEO of a company with a pretty cool name called Simpleology.  And Simpleology, which I’ll put a link to in the show notes is a special web application, which kind of sounds like a boring name because I’ve checked it out and it does more than what it sounds like, but it’s a web application that helps people and teams get more done faster.  And Mark has started over 30 different start-ups including things like Search Hound and ROI Bot, Start Blaze, Neurogizers, and just a ton of things that kind of help people make their lives better.  So, we’re pretty honored here to have him on the show.  So Mark, welcome.

Mark:  Hey, thanks for having me, Ben.

Ben:  So Mark, I’ve got a book in front of me that you wrote and I’m going to put a link to it in the show notes for people, but it’s called “Do it Yourself Nanotech Super Nutrients” and the subtitle is: The Tech CEO’s Unfair Advantage.  You delved into some stuff in this book and I wanna kind of get into some of the things that are in there.  But first, since we’re going to be talking about biohacking, Mark, how would you define a biohacker?  Like, what is that to you?

Mark:  It’s a great question.  I don’t know if there’s any agreed upon definition for that now.  It’s just…  It’s one of these movements that is sort of taking on a life of its own.  Similar to a way that transhumanism, right, you know, if you were to ask a bunch of transhumanists what is transhumanism, you’re probably going to get a bunch of different answers.  So, with that caveat, what biohacking is to me is sort of a sensibility whereby you understand that you can quantify and measure things going on in your own health and take responsibility for those things yourself even though you are not a member of the generally accepted medical community.

Ben:  Gotcha.  Gotcha.  So, you don’t have to be an aluminum foil hat wearing nerd to be a biohacker.

Mark:  You don’t have to be a nerd, you don’t have to be a medical professional, but you’d better have a brain or else you’re going to be a dead biohacker.

Ben:  Now, I think a lot of people think about biohackers as these dudes and gals who are running around just doing crazy things to their body, right.  You know, injecting stuff or doing cranial feedback and electrocuting themselves, I mean, are biohackers just a bunch of crazy druggies who kind of haphazardly put any compound into their body or is there kind of a science to this stuff?

Mark:  Well, some of them are.  But, it varies from person to person, right.  You know, there are things that a biohacker would do that the average guy would consider is quite bizarre and quite strange, it all depends on your value system, right.  But, with that said, for the most part, most of the biohackers I know are super smart, are super responsible.  Yeah, they do stuff that’s outside of the norm, but they do it very thoughtfully.

Ben:  Mm.  So, do you consider yourself a biohacker?

Mark:  I would say that, probably since I was 5-years old I was a biohacker without even knowing it.  But yeah, I think that label is probably pretty fair for me.  Yeah, I’m that among many other things, but yeah.

Ben:  Gotcha.  And so are you… when you do some of the things that, for example, you talk about in this book or we’re going to talk about as we have a conversation today, are you doing things like tracking and quantifying as you go or are you more one of those qualitative people or do you actually have systems in place to test things you go?

Mark:  That’s a great question and it depends on how much free time I have and… which is usually very little right now because I don’t really have a lot of free time, I’m just so heavily involved in the company that I’m building.  I am more of these qualitative guys.  I definitely do measure things on, you know, I’m in the VA Medical System as a vet and that’s not really enough.  So, I go out and get some other tests on my own.  But I’m not obsessive about it, right.  Like, I don’t get the data, change one little variable, and then check it out again.

Ben:  Right.

Mark:  That’s… you know, hey, if you’ve got the time to do that, that’s definitely the way to go, but you need to be very aware of the fact that you can’t quantify everything that’s going on in a way that causality can be meaningfully measured.  And by that I mean, there are so many things going on in your life and in your body that if you change one parameter there are probably a bunch of things that have changed that you haven’t yet been able to measure, maybe that science is not even aware of yet.  So, you have to have that type of caveat.

Ben:  Right.  Yeah, yeah.  I’m kind of in the same boat with you in that I really do like to try out, kind of the cutting-edge science tools that come our way to make our bodies better, but I frankly don’t have a ton of time to do things like, the CNS Tap Test on my iPhone and logging everything over at QuantifiedMind or heck, I have a hard enough time using EverNote.

Mark:  What!

Ben:  So, yeah.  I’m kind of there with you in that I do try and listen to my body as I do some of these things and I think that people should be aware that they don’t have to walk around with their iPhone like, strapped to their check 24/7 as they type in all their data to see how their body responds.

Mark:  That’s right, but one thing I’ll say is, we’re getting to a point where biometrics are going to be so easily and ubiquitously measured.  It’s kind of a biometric revolution going on right now.  You’ll be able to, with maybe one tiny sensor, be able to measure thousands of things that would have cost you probably tens of thousands of dollars to get any formal testing on.

Ben:  Yeah…

Mark:  We’re almost there.

Ben:  Oh, I know.  Every Tuesday, I test my blood, which two years ago if you asked me that, I would’ve been like, no, that’s a thousand bucks every Tuesday.  But now, I literally do a drop of blood on this little card and send it off to a company and they run in through a mass spec and right now they test 16 different biomarkers, but I was speaking with the CEO of that company a couple of months ago and she was telling me how we’re really not that far away from like, an implantable kind of chip in your wrist that could do the same thing and just feed data as you go.  So, yeah.  I think that it will get easier for sure.

Mark:  Yeah, that’s so exciting.

Ben:  Yeah.  So, let’s jump into some of the stuff that you talk about in this “Nanotech Super Nutrients” book.  You start off with the idea that maybe popping pills, which is something that I think a lot of biohackers or even like, the health conscious people who are listening into this show who are maybe using lots of supplements are doing.  But, why is it that the people who are kind of on the cutting-edge nowadays are maybe popping pills a little less?

Mark:  Great question.  Well, the delivery systems have improved tremendously and most people are not aware of the advances in delivery systems and unfortunately there are still a lot of companies out there that for whatever reason, are still selling a lot of things that are antiquated and that was another…  We get into that in quite a bit more detail in the book itself, but I’ll give you one example, and I know we’ll talk about this here in a minute, but the liposomal pathway of ingestion is just such an exciting thing and something that the pharmaceutical industry has known about for quite some time that there’s still paucity of liposomal medicines that have been approved.  Because why?  Because the approval process is very difficult and biohacking subsequently is sort of filling this gap in-between, the really reckless and irresponsible and ineffective nutritional industry and then the reckless and irresponsible on its own right pharmaceutical industry, but with better technology, right.

Ben:  Right, right.

Mark:  And they’re like, hey, you know what, let’s take all the good from all of those things and let’s find the best methods.

Ben:  So, what it comes down to is that people who really understand this stuff are kind of wrapping their heads around the idea that maybe when you swallow whatever, a multivitamin pill, you’re really not getting much at all out of it except expensive pee?

Mark:  Yeah, in most cases, well…  I don’t know about “most,” but yeah, maybe most.  You know, and if you look at the quality of stuff that’s out there, most of this stuff is not pharmaceutical grade, it’s combined with a whole bunch of different fillers.  It’s a compressed tablet that often doesn’t even dissolve, right.

Ben:  Right.

Mark:  So, not only is it not bioavailable, it’s not even chemically available.

Ben:  It just comes out the other end like corn.

Mark:   Yeah, that’s right.

Ben:  Interesting, so let’s talk about some of these alternative delivery mechanisms for people who want to maybe kind of jump down this rabbit hole and look into doing things other than just kind of grabbing pills off the shelf of Costco.  Let’s start off with something you just talked about, this liposomal delivery.  What is that?

Mark:   Yeah, so it’s a really fascinating thing.  Basically, it’s the encapsulation of a molecule around some fat, more or less.  Normally the fat is a phosphatidylserine which is freely available in lecithin.  And, what happens is it tricks the system into getting that substance directly into the blood.  So, one really interesting example is that of glutathione.  So, glutathione is a peptide that is usually broken down to its base amino acids components through the digestive system.

Ben:  Right.

Mark:   Because we’re not normally ingesting it that way the body says, hey let me build my own glutathione with the base components.  So, to avoid that particular problem, you disguise it with this layer of phosphatidylserine and the body says “ahh, yummy phosphatidylserine, I can use that!”  Goes right into the blood, uses the phosphatidylserine and then poof, the payload is delivered and it’s directly in your bloodstream.  You have glutathione now directly in your bloodstream in a delivery mechanism that is some people say is more efficient than a direct injection.  I don’t have any real conclusive data on that, but that’s the general notion.

Ben:  And you see…  I’ve noted that people, like vegan and what… primarily like vegan athletes, like Rich Roll for example, they’re encouraging folks to do their vitamin B in that way as well.

Mark:   Yeah, yeah.  There’s all sorts of different supplements that are being handled in this way.  Now, this is something that I talked about in the paper and maybe one of your listeners is the right person to hear this, but what we need is a very conclusive database showing what different types of nutrients in what forms are encapsulate-able via the liposomal delivery mechanism and also we need people doing research on what are the best methods, what are the best substrates here for liposomal encapsulation, what are the best manufacturing methods that people can use at home?

Ben:  Right, right, because this is something you mention in the book as well, these are things that people can, if they want to, do at home.  You can actually get this fat mix that you can mix up and within a spray, spray certain vitamins into your mouth and deliver them liposomally if you learned how to do it right, correct?

Mark:   That’s right.  Exactly.  And here’s where it’s a little bit fuzzy, right, and this is where the biohacking community sometimes goes a little bit off into the deep end, but it’s very thoughtful about it.  You know, there aren’t a lot of data sets out there that show that the do-it-home liposomal encapsulation method is as effective as some of the methods that have been used in the industrial applications of this.  So, we need more data on that, but what where biohacking comes in very handy here is it says, well we understand the science behind this.  We know theoretically this makes sense.  We can actually observe the liposomal encapsulation has occurred, but there isn’t a lot of comparison out there of the effectiveness of this compared to, say, a professional company that has created their own liposomal formulation.

So, that’s another area of data that we need and hopefully someone really smart out there can do a lot of comparison there and post the results so that the world can benefit from this.

Ben:  Right, yeah.  It’s interesting and just from a personal experience standpoint, I’ve tried the liposomal glutathione.  Hearing about it from another biohacker, Dave Asprey, and used some of that at a time he encourages folks to use it, which is just when you’re drinking a lot of alcohol, and certainly noticed that I woke up feeling a difference, but never compared it to a pill-based form of glutathione, you know.  Even though it’s certainly purported to be far more biologically available when delivered liposomally like that or sprayed into the mouth.

Mark:   Well, one quick thing on that.  I can tell you with a fairly high degree of confidence that  a pill form of glutathione that is not liposomally encapsulated, like if you just buy straight glutathione in a tablet, I mean, that’s a huge waste of money.

Ben:  Yeah, yeah.  That’s good stuff for people to know because I know a lot of people are buying detox supplements for that glutathione specifically.

Mark:  Yup, yup.

Ben:  Yeah.  Speaking of spraying stuff into the mouth, let’s talk about another method of supplement delivery that you talk about called nebulization.  Can you get into that?

Mark:  Yeah, nebulization is really awesome and I’ve had some great experience where I was able to trip up a lot of really great biohackers on this because they think I’m talking about vaporization, but they don’t actually know what it’s all about which is cool.  It’s not super uncommon.  Folks who are asthmatics use nebulizers often to deliver albuterol and things like that.  It’s definitely well known, it’s well recognized.  The pathway is well understood.

Essentially what you do if you get distilled water, you run it through a nebulization machine and it vaporizes… well, not vaporizes, it nebulizes the water so it creates particle sizes of about anywhere from maybe 4 to 30 nanometers in size.  Now, there’s certain sizes that are effective and certain sizes that are not.  So, you’ve got to get a nebulizer that is actually of a size that is effective for what you’re putting in there.  But what you have to do is dissolve a particular component and these have to be a particular molecular weight and particular dissolvable to particular sizes themselves.  You dissolve it in that distilled water and then you run it through the nebulization machine and then you simply inhale it.  And if you know that the component sizes are correct, you can very, very effectively deliver a number of things into your system.  And the one, again, that’s very interesting is glutathione.  Now, this isn’t something that’s recognized in the traditional medical community.  You don’t see it out there, but the alternative medical community uses glutathione nebulization quite a bit.  And we know that because the molecular size is of a compatible size, that you can actually nebulize it effectively.  Theoretically, alright.  Now, I trust the process enough myself to actually use that, because it’s way easier than doing my own liposomal encapsulation.

Ben:  So you have a nebulization machine in your kitchen, or whatever, and that’s what you’re using?

Mark:   Yup, I have a little tiny one.  In fact, there’s only one that I’ve found that BPA-free.

Ben:  Well, that’s good to know.

Mark:   Well, yeah, you know about BPA I’m sure you’ve guys have talked about that on your podcast.

Ben:  Yeah.

Mark:   I mean, it’s an endocrine disruptor.  Really bad news.  It’s kind of a shameful thing for humanity that we’re allowing it to be used so often.  But, I’ve only been able to find one.  I don’t remember the name of it right off hand here, but it’s there in the report.

Ben:  Okay.

Mark:   Now, I would like to get, hopefully someone out there listening could come up with this, but I would like to get an ultrasonic nebulizer which nebulizes to smaller particle sizes than the one I have that is also BPA-free.  I don’t know of one.  If one does exist or if someone could build one, that would be a great service.

Ben:  You know, up until this point in my life, I’ve never actually heard the term ultrasonic nebulizer, but I’m going to add that to my vernacular.

Mark:   That’s right.  We should be talking about this freely.

Ben:  That’s really interesting.  So people can just buy a nebulizer?  You just need to make sure it’s BPA-free.

Mark:   Yeah, yeah.

Ben:  Okay.  Interesting.  So, let’s talk about something else.  Vaporization.  What is vaporization?

Mark:   That’s another really, really interesting thing.  So vaporizers are commonly known about in the medical marijuana community, for example.  Now, for folks listening, if they got some social hang up over marijuana, I would say, read the science on that.  Maybe examine your feelings about it.  See if it’s based on science or if it’s based on just a general fear through propaganda.  Not to really get too deep into that conversation, but I would say that compared to alcohol, it’s probably a much, much safer.  Talk to your doctor about that one, especially if you’ve got psychological issues.

But, the point here is that people use that device to take their medical marijuana and pull particular chemicals out of it.  Because, certain chemicals have certain vaporization points.  Now, the vaporization point is a temperature at which certain solids inside a particular item will turn into a vapor.  Now, this is before the critical point where it turns into a straight gas and when it hits that point, you can breathe it in and ingest it into your system very, very precisely.  Now, I’ll give you a really interesting thing here about this.  And again, if there’s anybody that’s hung up about using pot as an example, I apologize if that offends you, but, let’s just look at it from…

Ben:  I live in one of the two states where it’s legal, so…

Mark:   Yeah, you guys are kind of over it now.  Yeah, and I think we all should be.  I’ll give you one really specific reason why.  So, the example is there is a component in there that… one of the chemicals is a very, very effective analgesic.  A very effective pain killer and the vaporization point of that is lower… or, I’m sorry, it’s actually a little bit higher than the THC vaporization point.  So, CBD is the analgesic.  THC is one of the well-known psychoactive compounds.  So, what you can do with medical marijuana is you can vaporize out all of the THC.  Well, I say medical marijuana, it’s now legal recreationally in Washington State.  But, you can vaporize out the THC and then one of the things that’s left is the CBD, the cannabidiol.  So, without any psychoactive effects whatsoever, you can hand someone that de-THC medical marijuana or recreational or whatever and give them the precise temperature for a vaporizer and allow them to pull out the CBD from that without any psychoactive effects hardly at all.

Now, think about this, that means that you can at your home, have an analgesic- a painkiller- that is far safer for you than opiate painkillers, but is also extremely effective.  That is… Man, if I were someone that were a cancer patient or anyone that was under any kind of chronic pain and doctors were telling me to ingest opiates and become addicted to opiates and to experience the long-term damage that’s going to occur to me from being addicted to opiates, I would say that’s a pretty hopeful thing.  This pathway, vaporization, is open to many, many different types of compounds.  So, it’s very exciting.

Ben:  Interesting.  By the way, I should point out to those of you listening in to this part of what Mark is saying, if you do happen to be, because I know we have a lot of people who are doing like, Ironman triathlons and marathons and stuff like that listening in, be especially careful with this stuff just because cannabinoids are a banned substance from the World Anti-Doping Association.

Mark:   Right.

Ben:  So, I don’t want anybody getting popped.  But, yeah.  I mean…  The point you make is super important.  Much safer than a lot of the pain killing medications out there and you can learn how to vaporize this stuff in the comfort of your own home.

Mark:   That’s right.  And, one other thing I’ll say to that for any of the elite athletes out there, while vaporizing something is far easier on the lungs than smoking something is, for example, you are still going to have some effect on the lungs.

Ben:  Yeah.

Mark:   And if you do irritate the lining of the lungs, your performance as an elite athlete could very well be effected.  Now, Michael Phelps may tell you, you don’t have too much to worry about, but there you go.

Ben:  And I should point out though that not everything that Mark and I are talking about are things that athletes can avoid.  You know, liposomal delivery of vitamin B12 is a perfect example.  I’ve personally gotten things like Meyers Cocktails before races which is just a bunch of vitamin B and vitamin C and you can get glutathione and it’s just basically one of my neighbors, who is a nurse, just gave me the IV.  And you can certainly do things like that and all of that is completely legal.  It’s like taking a multivitamin except a very, very powerful one that you feel surging through your bloodstream right away.  So, this stuff does work.  It’s just slightly less convenient than taking a bottle of pills out of your refrigerator, but holy cow, big difference.

So, let’s talk about another couple things that you mention in the book, Mark.  One is sublinguals.  What are sublinguals?

Mark:   Sublinguals are nutrients that can be absorbed under the tongue.  So basically, you get a liquid or a solid of many, many different varieties of forms.  You put it under the tongue, you let it dissolve or you just let it sit there for a little while.  It goes straight into the bloodstream.

Ben:  Mmm.  So, how long would someone actually put some in their mouth if they were going to dissolve something sublingually?  Is there a certain period of time that you would hold something in there.

Mark:   It depends on the delivery mechanism, but it’s usually no longer than a couple of minutes.

Ben:  Okay.  Got it.  Do you have an example of something that someone could find that would be use sublingually?

Mark:   Yup, a really great example that everyone can benefit from and can actually make themselves are the form of tinctures.  And tinctures are simply where you take usually an herbal substance and you dissolve it in some kind of alcohol.  I would recommend vodka because it’s one of the cleaner forms of alcohol and it’s intended for human ingestion.  And then you let that herbal substance sit in that alcohol for sometimes up to weeks, shaking it once or twice a day and many of the bioactively available compounds are transferred into the alcohol and then some of which, not all of which by the way, some of which are absorbable by the sublingual pathways.  So, you would put a couple drops of that whatever it is under your tongue, some of that’s going to go in.  You swallow the rest.  Some of the rest would get into your blood through the normal pathway of your digestive system.

Ben:  Gotcha.  I actually do some essential oils and tinctures.  I get from a certified organic company or through my naturopath, but things like astragalus and echinacea and oregano and some of those immune boosters, you can get in tincture form and I know that all of those, most of them instruct you to hold for like 30/60-seconds sublingually then you just swallow with a glass of water.

Mark:   Yeah, and I’ll tell you what, one way you can get the cost down on that is to buy herbs in bulk.  There’s some really great websites out there that will sell fairly high quality herbs in bulk form that will cost you maybe 10% or less of what you would pay for a premade tincture, but there is the labor involved in doing it yourself.  So…

Ben:  And so you’re basically just mixing those herbs with an alcohol to get the extract?

Mark:   Essentially.  Yup.

Ben:  Interesting.  I know you’re get into more detail in this in the book.  So, folks who want to read more, we’ll definitely link out to it in the show notes.  Let’s talk about transdermals.  We’ve actually talked about this a little bit on the show before, Mark.  We’ve talked about transdermal magnesium, but talk a little bit about transdermals and how that works.

Mark:   So, transdermals are really interesting.  They will be absorbed directly through the skin and it’s interesting but also one of the scariest forms of all.  So, some things are absorbable transdermally in their natural state, some need to be mixed with some other delivery mechanism, for example, one of the most common ones is DMSO.  Right, dimethyl sulfoxide is a solvent.  It’s used quite a bit in veterinary medicine.  It has this really amazing but scary property whereby things of a particular molecular weight will be dissolved into the substance itself and when you apply that substance to the skin, goes straight into your bloodstream.  Super exciting in some cases, super dangerous in others because if you were to accidentally mix certain things into your DMSO mixture, for example, mercury, which is of the correct molecular weight to be distributed via DMSO, you will give yourself a very nasty case of mercury poisoning which is something you absolutely do not want because if it doesn’t kill you, it will give you lots of long-term health problems.  So, proceed with extreme caution with transdermals.  There are a lot of people out there who do it in a very cavalier way.  I would just tell them, “Wow, man.  Think about what you’re doing.”

Ben:  Yeah.

Mark:   It may have worked for you up to this point, but it only takes one big accident to do it the wrong way.

Ben:  Yeah, because magnesium is kind of likes child’s play compared to some of that stuff.  I remember reading the book “The Doper Next Door” by Andrew Tilin who’s a recreational cyclist and he started using transdermal testosterone cream for enhancing his performance in cycling.  And, he actually started to freak out because his kids got their hands on his transdermal hormone replacement and that can like destroy children endocrine systems.  So…

Mark:   Yup.

Ben:  Certainly, folks, and I know that you say this in the book too, Mark, don’t screw around and kind of do your research and understand what you’re working with before you mess around with any of this stuff.  So…

Mark:   I can’t emphasize this enough.

Ben:  Yeah.

Mark:   Really.

Ben:  Now, I want to mention something else that you get into and I really like your approach to this.  So, I want you to talk about it a little bit and that’s detoxing.  Like, your approach to detoxing is kind of cool.  So if you were going to detox, Mark, how would you personally do it, what would be your ideal detox?

Mark:   So, the way I look at it is there are several different components that have to be addressed and most of the detox products out there don’t understand all these different pathways.  So what I would do is I would concoct a combined approach that includes the following.  One is you’ve got to stop poisoning yourself whatever that source of detoxification is in your body, you better get it out of there and it could be a number of things.  It could be, that you’re eating junky food, which, hey, I understand, right.  We do this, we like our foods, but there is a consequence, there is a cost we have to be aware of that.

Another one can be sort of a systemic form of toxicity that’s coming from, say for example, a fungus that’s growing in your body, right.  A candida infection is going to be a source of toxicity up until the point where you get the overgrowth handled.  Now, there’s always going to be a tiny bit of candida in your body, I think it’s biologically required for certain things, the overgrowth is the problem.  And by the way, subsequently, a lot of biohackers talk about this, things are not necessarily inherently toxic in themselves.  They can be toxic at particular doses, right.  So for example, if something is a cholinesterase inhibitor, could be very beneficial at one dose, could be deadly at another, right.  So, candida overgrowth is constantly poisoning you if you’re not careful.  You’re gotta…  Another thing could be maybe there’s BPA in your house.  Maybe there’s a mold overgrowth – that’s something Dave Asprey talks about, one of the really great things that he’s done is made people very aware of the problem of microtoxins.  Great service he’s doing for folks.

So, that’s the first thing is to stop poisoning yourself.  Very complicated topic.  It’s something I think every human being alive needs to educate themselves about and needs to be aware of, not just for themselves, but for their children too.

The next thing is you need to have some form of glutathione S-transferase probably boosted in your system.  So the third pathway, which is to boost glutathione is not going to be nearly as effective as it would be if you’d combined it with a method of boosting glutathione s-transferase.  There are number of ways you can do this.  Turmeric is one.  Gerson therapy, which really gross, we won’t talk about it here.  Google it at your own leisure, but remember I warned you.  But, hey.  It’s also something a lot of people say is curing them of cancer, so…  let’s not be too provincial about this stuff.

Ben:  Yeah.  We actually talked about it on a podcast a couple of years ago in detail, the Gerson therapy, so…

Mark:  Oh, you have?

Ben:  It’s out there folks if you want to go to BenGreenfieldFitness and google it, you can find it there.

Mark:  Yeah, I would say, we’ve got to get over some of the weird hang ups we have about things and just understand our health, you know.  The hang up is a social convention that we invented as humans has absolutely nothing to do with bioactivity or the effectiveness of anything.  So anyway, do with that information as you will.

The next thing is you need to have some way of binding these toxins, okay.  So toxic binders are things that will actually attach themselves to a particular toxin and then allow themselves to be pushed out of your body now.  So, without the binders, the toxins are sort of floating around freely; with the binder, it attaches itself to it and then gets itself set up for a pathway of elimination.

So, the fourth… the final thing that you need to do there is you need to find some way…

Ben:  Hey, Mark, can I interrupt you for just a second?

Mark:  Go for it.

Ben:  What’s an example of a binder?

Mark:  Ah, great!  Thank you.  Well, I’ll give you a couple of them.  So, chlorella is a great one.  Let’s see…  Bentonite is another great one.  Charcoal is another great one.  Now, charcoal really great example of charcoal here, right.  Now, the medical community will tell you that the body does not need your help in detoxifying yourself, but you can know on the face of it that this is simply not true and that the medical community itself does not believe in this.  Why?  Because the medical community recognizes that, yes, there are toxins and yes your body needs a little help in eliminating them if they’re getting to a point where they’re becoming a serious health risk and sometimes even deadly.

Charcoal is known as the universal antidote in a lot of emergencies room.  It binds to a lot of toxic substances.  Now, by the way, there’s a technical definition difference between toxins and poisons, you don’t really need to worry about any of that, really.  You can look these things up, but charcoal will bind to toxins and poisons of various types very effectively and will flush… it will line those things up to be flushed out of your system.  Yes, the medical community does recognize that even if your doctor tells you that they don’t and that example that I gave you is irrefutable proof that even the most conservative medical community understands that certain things must be detoxified from your body.  Now, why is that whole riff important?  It’s important because the medical community has not yet classified and identified a lot of things going on in your body.  Industry is creating things faster than the medical community can respond to them and because of that, there are a lot of as yet unidentified biological consequences going on in the body.  One of them, I believe, is an excessive toxic load that is a combined effect of mycotoxins, toxic substances like BPAs and other industrial byproducts that are seeping into your body.  When they get to a point where your body cannot bind and flush them out fast enough, that I think is the cause of a lot of illness and if you help the body in that process, it can clear up a lot of issues that you may have.

Now, this is a very fuzzy area, the amount of data on this is not anywhere near enough, but do your own research and I think that if you think about it deeply and you research it deeply enough, you’ll come to similar conclusions.  But, that’s up to you.

Ben:  Interesting.  So, I interrupted you and you were getting to the last step of the detox.

Mark:  Yup, and thank you for that interruption because that was a very important point that I was going over there.  So, the final point is to help the body flush these things out.  So, let’s say you’ve bound all of these things or you’ve deactivated them enzymatically and/or you have helped the body detoxify them or oxidize them with thinks like glutathione, your body still needs to eliminate them.  Your body normally eliminates them through sweat, through urine, and through feces if you speed up that process by doing things such as [38:55] ______ cleanse which has other beneficial effects of cleaning out the lining of the colon or by taking something like psyllium husks or taking something like senna leaf, what will happen is that elimination process will be accelerated.  Those things will get out of your system a lot faster rather than, you know, linger around in your digestive track for a longer period and in some cases, when they are lingering around the digestive track, they are still effective as toxins and so you’re still poisoning yourself more or less.  So, speeding up that process is sometimes essential.

Ben:  Interesting.  Okay, got it.  So, basically you get stuff like glutathione into your body and then you do what you call potentiating it through using something like say curcumin and then you bind using chlorella or charcoal or bentonite or something along those lines, and then you basically flush the stuff out with something that’s kinder to your digestive system than like the high fiber extract.

Mark:  More or less.  And, what’s really cool about that model is that you can address those different pathways with a number of different interventions and come up with your own combination of things.  Most of the different detoxification methods you hear about out there, I don’t any of them that address all of those different pathways and I don’t know of any of them that have that level of flexibility.  So, that’s why I came up with that model and why I prefer it.

Ben:  Yeah.  Well, folks, if you’re listening in, this guy that we’ve been talking about, this “Nanotech Super Nutrients” guide that Mark wrote, it’s pretty simple.  It’s like, 40-pages long and it’s free.  We’ll put a link to it in the show notes where you can go grab it and read through it.  Super-duper interesting stuff.  Mark’s got kind of a cool style of writing that keeps things really simple, and Mark, I also wanted to kind of get into, just for a moment, you know, we’ve talked about biohacking but in the realm of productivity hacking in general, I know you’re kind of an expert at getting more done in less time and really simplifying life.  So, I wanted to make sure that I asked you about the Simpleology and what exactly Simpleology is.

Mark:  Yup, thanks for asking that and before I answer that, one quick thing about the guide, there’s also a companion guide that’s not advertised on the page that Ben’s going to show you, but there’s another report/guide that I wrote called Reverse Engineering The Limitless Pill which is showing some of the state-of-the-art stuff going on in boosting human intelligence.  There’s a lot of really exciting stuff that’s going on with that.  It shows you what I believe so far the most effective neurotrophic substances and the different, you know, mechanical ways you can address that.  So, that same URL that Ben’s going to give you in a second will show you how to get that as well and that’s all combined and that’s all free.

Ben:  Awesome.

Mark:   Simpleology is, like you said earlier, it’s a web app that doesn’t sound too sexy, but it’s a more or less tool to help you get more done faster.  But, the way it does it is the unique and interesting thing and that’s that it does it through the process of aggressive simplification.  Everyone understands intuitively that simplifying things is very, very powerful for a number of reasons.  One is, if you haven’t focused in on a small number of effective actions in your life, it’s like the difference between a laser and a flashlight, right.  A laser can cut through steel, a flashlight cannot.  You can turn yourself into a laser as a person if you zoom in on the right things.  And Simpleology is a tool- helps you aggressively do that.

Now, the other thing is it’s like this, you’ve only got a certain amount of time in your life and you can be that jack-of-all-trades who’s constantly distracted by Facebook and TV and every other things that comes across your path, at the end of the day, you probably don’t feel too good about yourself when you live that way.  If however, you take control of your own time and of your own productivity, you tend to feel pretty good and satisfied about yourself and you tend to move a lot closer to the things you want in your life a lot faster.  So, what we do is we have a simple process that guides you through that process of aggressively simplifying things in your life just by clicking the little link and following the prompts.  And at the end of the whole process, you’ve got a very clear of what’s important for you that day.  It’s combined with a number of other tools that are based on the same level of science that we’ve been talking about with all of these different substances.  You know, we’ve done the same number of research, if not greater research, into human psychology, organizational psychology to help you optimize the function of your brain throughout the day to eliminate as many distractions as possible and to make you as absolutely effective as you can possibly be.

Ben:  I love it.  It’s cool and I’ll put a link in the show notes too if you’re listening in, go check out the Simpleology homepage.  I am a huge fan of keeping life simple.  For me, I know, training for Ironman and chasing my boys around and trying to get a lot done, simple is a good thing.

Mark:  Yup.

Ben:  So, Mark’s really got it down and you know me, listeners, if you’ve been listening for a while, I’m always kind of souring the web to find the best stuff that’s out there when it comes to enhancing your life, your health, your fitness, your productivity, and your performance and this is certainly something I’d vouch for.  So, check it out and all of that is going to be over at BenGreenfieldFitness.com in the show notes for this episode.

Mark, that was super cool and I’m kind of a geek, so I love this stuff.  But I think the listeners are going to dig it as well.  So, thanks for coming on the call today.

Mark:  Thanks for having me.  I really enjoyed that.

Ben:  Alright folks, until next time, this is Ben Greenfield and Mark Joyner from Simpleology signing out from BenGreenfieldFitness.com.



News flash: lots of pills, capsules, tablets, and vitamins end up completely unabsorbed, in a pile of poo, in your toilet.

From liposomal glutathione to transdermal magnesium, the truth is that there are delivery mechanisms for vitamins, minerals, nutrients and any other pills you may be popping that are 5 to 20 times more potent than regular delivery mechanisms like simply swallowing a capsule or tablet.

But although they can literally give you a nearly unfair advantage when it comes to enhancing your performance, detoxing your body quickly, massively boosting your immune system or sparking a significant increase in your IQ…

…these delivery mechanisms fly under the radar.

Not anymore.

In today’s podcast interview with Mark Joyner (pictured right), you’re going to learn everything you need to know about how to deliver important nutrients to your body in much more efficient ways that simply popping a pill…

Mark is the author of the Do-It-Yourself Nanotech Super Nutrients Guide and the biohacks, detoxes, and nutrient delivery mechanisms we discuss during the show (which he details in the guide) include:

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-liposomal delivery






-and much more.

Mark is an author, inventor, and serial entrepreneur. He is Founder and CEO at Simpleology, a web application that helps people and teams get more done faster.





Ask Ben a Podcast Question

2 thoughts on “[Transcript] – Are Your Expensive Multivitamins Even Absorbed…Or Are There Better Ways To Deliver Precious Nutrients To Your Body?

  1. David Kim says:

    Hi Ben,

    Could you share your thoughts on how much credibility you affrod towards “Nano Glutathione” from Nanoceuticals?
    I asked them how their product compared with the lipsomal delivery method and here’s the answer I received.

    Liposomal GSH encases the GSH molecule within a fat lipid with the goal of protecting it from being destroyed in the digestive tract. Nano Glutathione approaches the same problem just from a different angle.

    Each Nano Glutathione particle is a minimum of 20,000 times smaller than normal delivered in a sublingual liquid, which passes through the mucous membranes of the mouth and into the bloodstream. This bypasses the gastrointestinal tract, where traditional oral GSH is broken down and destroyed before absorption. Research has shown traditional oral GSH to be largely ineffective raising GSH levels in the body. An independent university study that was recently completed on our Nano Glutathione product showed an 466% increase in blood levels over baseline after just one dose. Here is a link to that study: https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0215815&fbclid=IwAR2vzZjfV7bOjnxSSzjefEFQoH4VxbRZycTMtcl531ifUi_cxOn83x8B484

    Our permeation study shows 83% of each dose is absorbed after 90 seconds contact with the mucous membrane of the mouth. Liposomal absorption rates vary from study to study, but I have yet to see a Liposomal absorption rates above 40%.

  2. Christopher Swain says:

    Do you have any information regarding the risk factors associated with asthmatics using the nebulizing glutathione?

    The one study which is widely referenced suggests it is contraindicated but was a small sample and doesn’t look conclusive.

    Many thanks

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