The Surprising Science Of Injecting Young Blood, Salmon Sperm & Stem Cells Into Your Face (And Other Places) With Dr. Khanh Nguyen

Ben Greenfield [00:00:00]: My name is Ben Greenfield, and on this episode of the Boundless Life podcast.

Khanh Nguyen [00:00:05]: Young Plasma Exchange is removing the old plasma. But the step beyond that is instead of replacing with albumin or normal saline, we replace with young plasma.

Ben Greenfield [00:00:20]: Welcome to the Boundless Life with me, your host, Ben Greenfield. I'm a personal trainer, exercise physiologist, and nutritionist, and I'm passionate about helping you discover unparalleled levels of health. Health, fitness, longevity, and beyond.

Ben Greenfield [00:00:40]: Welcome to a field trip episode. I'm here at Austin Regenerative Therapy, and you may recognize that name from a previous podcast I did with Dr. Wen. This is kind of like the place where you go for aesthetic anti aging and sexual rejuvenation protocols. And I've got Wyn in the hot seat once again to talk about you. Young plasma exchange versus replacement. The P shot, the O shot, Botox VSEL, and something called the Neo7 peptide protocol. Funny in this juicy episode.

Ben Greenfield [00:01:15]: So the show's gonna [email protected] Austinplasma. Let's go talk to Dr. Nguyen. All right, so here we are in Austin again, round two. And if you're listening and you didn't hear round one, basically I am here regenerative therapy with Dr. Nguyen, and I'm doing my second round of young plasma along with some other goodies that we'll talk about. So this is kind of like the hub of, like, aesthetic and sexual rejuvenation along with anti aging treatments. And you guys are awesome.

Ben Greenfield [00:01:52]: Like, you've taken such great care of me and my wife this week, and I want to take a deep, geeky dive into some of these things that you do, because people have seen it on Instagram. Instagram. And they've heard me talking about it. But let's just jump in with this, the plasma thing. So people hear about. What's it called? Ype, Young Plasma Exchange. And there's a lot of places you can do. I've done it.

Ben Greenfield [00:02:23]: My wife's literally doing it right now here while we're talking. She's in the other room doing young plasma exchange. But I did young plasma replacement. What is the difference?

Khanh Nguyen [00:02:35]: Right. So actually, the. The plasma exchange is tpe. So it's tpe Therapeutic plasma exchange.

Ben Greenfield [00:02:44]: Okay.

Khanh Nguyen [00:02:44]: So most people talk about that, and it's more widely available.

Ben Greenfield [00:02:49]: Yeah.

Khanh Nguyen [00:02:50]: And that is a procedure. It's kind of like a plan. Cleaning your blood.

Ben Greenfield [00:02:55]: Oil change.

Khanh Nguyen [00:02:56]: Right. Where you're gonna be hooked up in a machine.

Ben Greenfield [00:02:59]: Okay.

Khanh Nguyen [00:03:00]: And then we'll remove the plasma part of your blood.

Ben Greenfield [00:03:04]: It's like getting really arm, pulling out.

Khanh Nguyen [00:03:07]: The blood and then replace with albumin or saline. So that's therapeutic plasma exchange. Right, Yoga plasma exchange. Is that meaning removing the old plasma, but the step beyond that is instead of replacing with albumin or normal saline, we replace with young plasma with actual human plasma. Plasma from young donors age 18 to 25. That's kind of the peak performance for humans.

Ben Greenfield [00:03:42]: Okay. So the therapeutic plasma exchange, when you're putting albumin back in, some people might not even kind of understand what that is. So what is plasma?

Khanh Nguyen [00:03:56]: Right.

Ben Greenfield [00:03:57]: In terms of the difference between that and just like blood.

Khanh Nguyen [00:04:00]: Right.

Ben Greenfield [00:04:01]: And then as a follow up to that, what is albumin?

Khanh Nguyen [00:04:05]: Right. So in whole blood that circulates throughout body, it has red blood cells to carry oxygen and then we have white cell count for infection, and then there's platelets for clotting and bleeding issues. And then the rest, which is a little bit over 50% of whole blood, is this gold liquid called plasma. Okay. And in that is a combination of protein, hormone, cytokines, and it's just loaded with the exosomes that we're going to talk about later.

Ben Greenfield [00:04:44]: The exosomes?

Khanh Nguyen [00:04:44]: Yeah.

Ben Greenfield [00:04:44]: And these are like the signaling molecules that help all your cells communicate. Is that different than extracellular vesicles or.

Khanh Nguyen [00:04:53]: Is that so Naso netatone? Yes.

Ben Greenfield [00:04:54]: Okay. Yeah. Because the big, I was looking at a big study on the plane on the way down here and it was like multi organ rejuvenation and this was rodent models. Because there's not a lot like a lot of good, like big long term human clinical studies on young plasma replacement for humans. But it was basically head to head compared against about, just about any longevity enhancing mechanism out there or treatment out there. It was head and shoulders for every single organ like the mitochondria and the brain and muscle tissue and bone. One of the most effective things that I'd seen in the literature. Yeah.

Ben Greenfield [00:05:29]: And bone. So this the, the plasma that you're putting in way different than albumin, even though albumin is good. Like if you're looking for like an oil change for the body, the plasma replacement, you're putting just basically the entire soup of biologics back to it.

Khanh Nguyen [00:05:45]: Mixture of biologic and it's. And the beauty of that is just like a perfect combination and it's coming from young donors. So, you know, so that kind of addressed the kind of like program age related decline. And then from that study, when you put in young plasma, you get the signal to tell the body, hey, start acting young again.

Ben Greenfield [00:06:13]: Yeah, yeah. Which I experienced. So that's why I'm here again. Like the last time I did it, people ask me like, what's the most effective intervention you've ever done as far as across the board, feeling better, like sexually, aesthetically, from a performance and recovery standpoint. And it was this, like that's why I'm back, honestly. Right, so the albumin though, what is that?

Khanh Nguyen [00:06:33]: Yeah, so albumin is just, it's just protein and we do that to create like that oncotic pressure so that that will stay in the circulation longer. So you're not gonna feel depleted and waiting for your body to make your own plasma.

Ben Greenfield [00:06:51]: Right. So if you weren't getting. Cause I mean a big part of it is just like the price. Right. It gets more expensive to get plasma, actual human plasma versus albumin. But if you were giving old plasma, you could still put albumin back in to replace some of what you'd taken out, right? Yeah.

Khanh Nguyen [00:07:06]: So it's just the whole space.

Ben Greenfield [00:07:07]: If I take old plasma out, what kind of stuff is in it? Like what am I actually pulling out? That would be bad.

Khanh Nguyen [00:07:16]: Right. So there's a mixture of senescent cells or zombie cells, byproducts, there's age related inflammatory and there's environmental toxicity, the microplastic, the auto antibodies. So it's all kind of junk. And the sicker you are, the dirtier your plasma.

Ben Greenfield [00:07:41]: Yeah.

Khanh Nguyen [00:07:42]: And so from my experience, when I treat patients, when I provide this for people with chronic condition, when they really tired, they're really sick, they can feel a big difference versus people that's doing it for longevity optimization. They feel more energized, they have faster recovery, better libido, better looking skin. But it's different when you have like chronic condition and you're just really tired and you can't function. It's a huge difference.

Ben Greenfield [00:08:17]: Is it true that in the US the state that we're in, Texas is the only state you can do this?

Khanh Nguyen [00:08:21]: As of now, yes.

Ben Greenfield [00:08:22]: Okay. Are they like pushing for legalization of it in other states? Do you know?

Khanh Nguyen [00:08:27]: They're working on that part, but it's, it's so I don't know. And young plasma is only available in Texas and with the protocol we do is a combination of removing plasma and infusing with young plasma. And there's only this place and maybe another clinic.

Ben Greenfield [00:08:50]: This place being like your clinic?

Khanh Nguyen [00:08:52]: Yeah. Because other places they do either TPE with human or they can remove a little bit of blood and then infuse with this.

Ben Greenfield [00:09:01]: Is this, this Is the same protocol if people watch like Brian Johnson's documentary Don't die. This is what he did.

Khanh Nguyen [00:09:07]: Exactly. Yeah.

Ben Greenfield [00:09:08]: Okay, so the, the, I guess like the big devil's advocate question, this is another question I get besides like, what's the difference between the exchange and the replacement is, well, how do you know that this is like good plasma? Or how do you know that your body's not going to reject it? So what's your response to something like that?

Khanh Nguyen [00:09:28]: Yeah, so the treatment of the practice of plasma infusion has been around for over 100 years. The safety profile is proven right. And for example, in 2019, there's like over 2 millions of plasma infusion. There's one preventable death.

Ben Greenfield [00:09:56]: You're talking about humans, right?

Khanh Nguyen [00:09:57]: Yeah. And from 2020 to 2021, there's zero death. And every day there's like over 6,000 of unit of plasma being infused or transfused. The difference here is we use young plasma and that is even have a stricter qualification. They screen and it's.

Ben Greenfield [00:10:25]: Yeah, that's what I was going to ask you.

Khanh Nguyen [00:10:26]: I feel like sex match and it's younger donor and they get screened. They have to be qualified.

Ben Greenfield [00:10:34]: Do you know what kind of stuff they're screening for?

Khanh Nguyen [00:10:37]: So it's the typical for blood related product. So all kind of viral, bacterial, infectious.

Ben Greenfield [00:10:48]: Yeah. Okay.

Khanh Nguyen [00:10:49]: Transmittable.

Ben Greenfield [00:10:51]: Yeah, it's kind of interesting. Like it arrives in like a cooler and you guys got to take it out. I thought one liter is five bags. Right?

Khanh Nguyen [00:10:57]: Right.

Ben Greenfield [00:10:58]: So I got I think 15 bags.

Khanh Nguyen [00:11:01]: Yeah, this time you 10.

Ben Greenfield [00:11:04]: I did 10 bags last time. I did 15 bags. So I got two liters this time, three liters last time. Something. This might sound like a dumb question, but I had one liter of plasma, like old plasma taken out, but then two liters put back in. How come that doesn't just overload the body with too much? Wouldn't you take out as much as you replace or does it matter?

Khanh Nguyen [00:11:26]: Yeah, so when you have a healthy heart and kidney, your body can handle and kind of, you know, adjust and there's. We do remove. Like I wouldn't give you like 3 or 5 liters at one time and you would go into valley overload. But that amount, it turned out to be okay.

Ben Greenfield [00:11:51]: Okay, so Dr. Nguyen, we had a podcast where you told your incredible story of like getting on a boat and escaping Vietnam and coming over here and at some point getting into medical school. Like, if you guys are listening, you gotta listen to the first story with Dr. Nguyen's background. I'm gonna link to that if you go to BenGreenfieldLife.com AustinPlasma BenGreenfieldLife.com Austinplasma and again, we're at Austin Regenerative Therapy. And so the plasma is kind of, it seems like, kind of like the flagship, like most expensive, fanciest protocol you can do. But in the spirit of really, really good medical tourism, I did some other things while I was just like here laying around getting the plasma, doing the treatment. So we were here three days.

Ben Greenfield [00:12:37]: My wife. And we'll go talk to my wife here in a little bit in this podcast and get her take on some sexual rejuvenation stuff you do for females and what her perspective is. But beyond the plasma replacement, another thing that we did was lasers and music and something called VSEL. So what is that protocol?

Khanh Nguyen [00:13:03]: So that is VSEL therapy and it stands for very small embryonic like. So these are the most primitive stem cells that the bone marrow in our body is still making. And they circulate throughout the body. However, they are not active. And scientists figure that they just made so that under stressful situation, they will become activated to help out. And now with that understanding, Dr. Todd Overkaitis, he discovered there's a way to activate B cells by using that particular laser. So we collect your blood, separate out the inactive B cell.

Ben Greenfield [00:13:52]: Is that just like with a centrifuge?

Khanh Nguyen [00:13:53]: Yeah, but it's a special kind of centrifuge. And then they get turned on on the tube with the special laser therapy, when we infuse back in the body and then guide it with the laser because it show on the test suit, the cells are attracted to the laser. And that's why we went through different area of the brain. The thymus. The.

Ben Greenfield [00:14:20]: Yeah. I sat in this chair for like 20, 25 minutes. So you took my blood out the first day I was here, you spun it, you concentrated these VSEL. You then use a laser, which I'm assuming stress them so they're activated. And then when you. And then the nurse. One nurse was pushing them into my body, just like a push iv and the other nurse was putting the laser over specific organ region. So the laser is that almost like drawing in like a homing beacon general.

Khanh Nguyen [00:14:50]: Area, because they are attracted to that. And so it's very intentional. For example, if people with type 1 diabetes and will trying to laser in the pancreas. Yeah, Right. And then for men who's still trying to be for fertility issues, that's when we shine to the testicles.

Ben Greenfield [00:15:11]: Yeah.

Khanh Nguyen [00:15:11]: Right. Or ovaries.

Ben Greenfield [00:15:13]: Do you ever get any pushback that it seems like, woo, woo. To be able to like use a laser to draw stem cells to an area or has Dr. Todd or anybody else done studies on this or.

Khanh Nguyen [00:15:23]: Yeah, so. So. Dr. Yes. So a, you know, I explain to patients clearly before we do anything and it's, you know, it's never any pressure to do anything that they don't clearly understand or believe in. And there are studies to show that VSEL IV therapy can reduce biological age by up to three years. And the other thing that I like about VSEL is that they're really, really tiny and so they can travel throughout the body, including the left brain area. So they can go into the brain because they're like two to four micro.

Ben Greenfield [00:16:13]: Yeah, yeah. It was not, I will admit, the most pleasant treatment that I've ever had in my life. But you guys injected stuff into my face, right. Was that VSEL.

Khanh Nguyen [00:16:26]: So what you had done was a very strategic combination of different regenerative modality. So we started out with laser with energy based. You had the sub ablative laser treatment and that is pretty much to create a control thermal energy injury to the skin and that turn on the repair and regenerate mechanism.

Ben Greenfield [00:16:57]: Okay.

Khanh Nguyen [00:16:58]: So that by itself is a great dancer.

Ben Greenfield [00:17:00]: It was a laser. What was the name of that laser?

Khanh Nguyen [00:17:01]: Neuroderm. Nuvaderm.

Ben Greenfield [00:17:04]: Nuvaderm. Okay. Yeah, yeah. And it has kind of. I was like, are they burning flesh out or. It's not that bad. But it kind of made like a sizzling sound as it was going over my face. It was like a mild, like a prickly sensation.

Ben Greenfield [00:17:17]: And so that's like causing mild skin damage.

Khanh Nguyen [00:17:20]: It's a controlled thermal injury. Yeah.

Ben Greenfield [00:17:22]: Okay.

Khanh Nguyen [00:17:23]: And it also has the ability to do ablative meaning it also target the top, the epidermis, endodermis. What you had done was sub ablative because we didn't want downtime.

Ben Greenfield [00:17:36]: Right. I had some other podcasts and stuff this week. You guys are on the.

Khanh Nguyen [00:17:39]: And it's drill effective as well. You just have to do more. So that is kind of like to start this cascade of regenerating and repairing. And then on top of that, we inject and we apply a concoction of regenerative biologics.

Ben Greenfield [00:17:58]: Okay.

Khanh Nguyen [00:17:59]: The young plasma B cell exosome. And they really together, they play well, they enhance the effect.

Ben Greenfield [00:18:10]: But you have, you don't just like do the laser and like smear that on the face that you're actually injecting those underneath the skin. Into the face.

Khanh Nguyen [00:18:17]: Right. It's intentional. And I want to target different layers of the skin, including the top as well.

Ben Greenfield [00:18:27]: How is that different than Botox?

Khanh Nguyen [00:18:29]: So Botox works by paralyzing the smooth muscle. Right. So it's just great for wrinkles. And then we talk about the. How it works for Botox, but for the skin is known for relaxing the muscle so that you don't have wrinkles, which is great. But what you had done is actually signal your body to reverse the aging of your skin by sending signals for the fibroblast to make more collagen and more elastin, more microcirculation. Right. So it's really making your skin younger.

Khanh Nguyen [00:19:15]: And to target all the age related collagen loss, damage, less microcirculation and therefore less nutrient to the skin. And therefore you have the age spot, the lines and the wrinkles and the sagging.

Ben Greenfield [00:19:31]: Does it help with like spots under the eyes, bags, things like that?

Khanh Nguyen [00:19:37]: The laser is amazing for a spot. Right. But around the eyes it just makes you look tired. Right. And I find that this is the best treatment by injecting and microneedling with all the biologic. Because it just naturally created, improved the collagen around that area without. Most people do filler, which, you know, it's just kind of not natural. And in time they kind of shift.

Ben Greenfield [00:20:10]: It and like the filler like kind of drops from gravity. Yeah, I've heard that. What would happen if you did that same mix of biologics, VSEL, exosomes and plasma into the scalp? Can you do that for hair?

Khanh Nguyen [00:20:22]: Yes. So we do the same mixture using the same principle on the scalp. And that stimulates more hair follicle, more circulation, more nutrient delivery to the scalp.

Ben Greenfield [00:20:38]: Yeah. The nurse was saying my beard might grow longer because you get on the face. We didn't do it on the head.

Khanh Nguyen [00:20:42]: Because you have a full head.

Ben Greenfield [00:20:44]: I have too much hair already. I don't want to do the Don King protocol.

Khanh Nguyen [00:20:47]: Right.

Ben Greenfield [00:20:48]: Okay. So we did all of that. We did the young part.

Jessa Greenfield [00:20:51]: Oh.

Khanh Nguyen [00:20:51]: And then we did the salmon sperm as well, which is the. Yeah, yeah. Which is another. Another great thing to add to it. And so that is the DNA from salmon sperm. And it turned out it has 95% compatibility with human skin. It's kind of interesting. And it's another very effective way to signal the fibroblast to make collagen and elastin.

Ben Greenfield [00:21:25]: Yeah.

Khanh Nguyen [00:21:25]: So the combination leading to glowy skin, more hydrated. And it targets all the fine lines on the sagging and even Deeper wrinkles you inject.

Ben Greenfield [00:21:38]: I thought that just like goes in the face like you hear it on the face. Yeah. So that wasn't in the needles that they injected on the skin.

Khanh Nguyen [00:21:44]: Right.

Ben Greenfield [00:21:45]: Okay, the. And is that actually like from actual salmon sperm?

Khanh Nguyen [00:21:51]: And they purify DNA from salmon too.

Ben Greenfield [00:21:54]: Okay, good. Yeah, I only want the purists to come in front of my face. So the whole field of longevity medicine seems pre shifted right now towards an interest in peptides. And I've actually done a lot of podcasts about peptides. I don't think it's any secret that I'm a huge fan of some of these injectable peptides, oral peptides, nasal sprays, et cetera. And in our last podcast you kind of hinted that you guys have this, this peptide protocol. And then we actually started into the process of doing it on this trip. Like you drew my blood for the special peptide thing that I had heard of before, besides briefly on our last show.

Ben Greenfield [00:22:36]: Tell me about the peptide thing that you do.

Khanh Nguyen [00:22:38]: Yeah, so first of all, like the, the peptide that we all know, those are off the shelf peptides and they very effective. I love them. I use all of them.

Ben Greenfield [00:22:48]: Yeah, we're talking like the BPC 157 and thymosin TB 500 and the stuff a lot of people have kind of heard of.

Khanh Nguyen [00:22:54]: Exactly. And they work great. But this is to the next level because those we know the specific action and we give the same peptide for everyone. Right. Neo7 bioscience number seven.

Ben Greenfield [00:23:12]: Like Neo the number seven, this is.

Khanh Nguyen [00:23:15]: Truly precision based personalized peptide and it's based on the analysis of your blood and your urine. And they look at your genomic, your proteomic, your biomarkers, your immune system. So exactly what's going on in your body. Okay, analyze that. And then they will rank all the faulty pathway by priorities. And then they design the peptide just for you to specifically fix those abnormal pathways.

Ben Greenfield [00:23:57]: So when you say they design peptides specifically for me, are these like peptides we all already know about and talk about and they combine them all together. Are they synthesizing they a new peptide?

Khanh Nguyen [00:24:07]: Yeah, they make the peptides just end up one just for you, just specifically. So these are made for your immune system, for your genetic, for your epigenetic, like whatever is going on in you up until now and then they will fix that.

Ben Greenfield [00:24:28]: How many peptides are we talking about? Do you know how many they combine together?

Khanh Nguyen [00:24:31]: So it's kind of like a combination is coming. 120 vials. Oh, and that and then you keep that. And that is like a year long program.

Ben Greenfield [00:24:42]: So these like get shipped to my house. And do they. Do I inject a certain thing on a certain day or how does it work?

Khanh Nguyen [00:24:48]: Yeah, so the protocol is you inject twice a week.

Ben Greenfield [00:24:53]: Okay.

Khanh Nguyen [00:24:53]: And then we start out low and see how you respond. And then we ramp up. And typically even within the first few weeks, people see a change in various things. Energy level, you know, cognitive function. And this is used initially for people with stage four cancer. And then now they keep on improving. And we are using this for different kind of autoimmune condition. Cancer, neurodegenerative condition is big.

Khanh Nguyen [00:25:33]: And then for like, for somebody like you, for resilience and longevity for optimization.

Ben Greenfield [00:25:41]: So the way that it works is someone were like come in here. I'm assuming this is one that is legal outside of Texas. Like you could. I'm assuming there's like certain practitioners around the US that would have this. It's called a Neo 7.

Khanh Nguyen [00:25:54]: Right. And so we have to apply for, is under a study protocol. So I'm a participant in that.

Ben Greenfield [00:26:02]: Okay. So that's, you can like legally do it.

Khanh Nguyen [00:26:05]: And then, and then we, you know, monitor and we track, you know, so it's very science based.

Ben Greenfield [00:26:13]: So you get your blood drawn, that gets sent off to the lab. And then they customize the peptide protocol. And then if someone does this, do the peptides just like show up at.

Ben Greenfield [00:26:23]: Your house every month?

Ben Greenfield [00:26:23]: They show.

Khanh Nguyen [00:26:24]: Yeah, yeah. So actually the whole protocol is really fascinating. It's pretty advanced, pretty complicated. So we collect blood and for people with, for you, it's resilience. You don't have anything going on, so we just collect blood. But other people with chronic condition, we collect blood and urine.

Ben Greenfield [00:26:44]: Okay.

Khanh Nguyen [00:26:45]: So that first thing that would get shipped to a specialized lab. And then they have this platform to look at your, you know, your, your whole exome signal and your rna, your immune system, your biomarker, your HLA typing. So they look at all that and then they send that to Neo7 and they have this very advanced platform which is a combination of augmented human intelligence combined with this. It's called precision based immuno molecular augmentation. And they just analyze and combine and then they will map out the faulty pathway and then they rank that and then they would then design the peptide based on the priorities, like which one is the worst and they were just going down. And for resilience, for what we, we collected blood for you, they will look at the eight different hallmarks of aging and they Rank that. And so, you know, like for example, for you, you're very healthy, you're very fit, but I'm sure you're going to have some kind of subclinical inflammation. Yeah, absolutely right.

Khanh Nguyen [00:28:11]: You're going to have some kind of mitochondrial. Mitochondrial dysfunction. So you know, whatever it is that is going on with you, they'll identify that and then prioritize. And then on the report it's really, it's eye opening. It's like a map of what's going on in your body. You're gonna see like, okay, on the information how bad it is, how high is it. Right. It's get ranked and then they from there then they design the protocol for peptides and then after that that will be shipped to the compound pharmacy for them to make.

Ben Greenfield [00:28:51]: Okay. So they have. Just because a lot of people struggle with this. I'm curious when it comes to something like long Covid or like the chronic inflammatory condition, is this something that could.

Khanh Nguyen [00:29:03]: Be effective for this is something that they added. It's kind of like it a test by itself as an option or like for you we, we did the add on option to also look at Spy X protein.

Ben Greenfield [00:29:17]: Okay.

Khanh Nguyen [00:29:18]: And look at the, you know, the side effect and then they can design the peptide to fix that. So it's pretty cool.

Ben Greenfield [00:29:27]: Interesting. So that would be like maybe like an anti inflammatory peptide or so like binding and removing or do you know?

Khanh Nguyen [00:29:32]: Yeah. So it just depends on what because the effect is different for everyone and it will show up. And that's why it's really personalized, you know, because like not everyone get affected the same way. And so whatever is going to show up for you, that's going to be addressed.

Ben Greenfield [00:29:51]: Yeah. And the whole time we're doing all these protocols, we're big fans of stacking. You're a big fan of stacking. You're running like red light. I'm inhaling hydrogen. You have the nanov device for reactive oxygen species signaling. You have a PMF mat running underneath me. Ivan brought my little electrical muscle stimulation pads and these stim the legs.

Ben Greenfield [00:30:11]: And we'll include plenty of photos and videos in this podcast as well so you can see what some of this stuff looks like. And then in this period of stacking, at one point when I was hooked up to my plasma, you guys had me wear a special skirt and you did the sexual rejuice stuff. I definitely want to get the female perspective on that. So we'll go talk to my wife. I was again doing the plasma exchange rate.

Khanh Nguyen [00:30:36]: I'm actually on my own.

Ben Greenfield [00:30:37]: Yeah. But tell me about what you guys do for sexual rejuvenation. Because I think you guys are pretty well known for like the sexual and the aesthetics part of things, right?

Khanh Nguyen [00:30:49]: So I. My background is critical care medicine and internal medicine, so I'm big on internally how to like, what's wrong, what's the root cause and then how to fix it and how to make people healthy, even aesthetically. You know, we work from the inside out. But at the same time, I'm a big fan of sexual optimization and aesthetic meaning, like, you know, you're healthy, but to look as good and as young as you feel, why not? And I'm a big fan of that, so. And I have a lot of fun doing that. The body is just like a huge massive network of like all these systems and it's all interconnected. And so I'm a big believer in stacking hormones, supplement off the shelf peptides, and the personalized peptide if people can afford. But in terms of the sexual optimization, you know, I address the, of course, the hormones issues, any medical issues, any psychological issues, any medication, just to be thorough.

Khanh Nguyen [00:32:07]: But the P shot in itself is so fun and it's really effective.

Ben Greenfield [00:32:12]: P shot is the man.

Khanh Nguyen [00:32:13]: It's the man shot and the O shot is the orgasm shot.

Ben Greenfield [00:32:19]: Okay.

Khanh Nguyen [00:32:20]: So yeah, and that is really effective. 85% or more men report improvement and very satisfied and come back.

Ben Greenfield [00:32:34]: What are you injecting into the man?

Khanh Nguyen [00:32:38]: Right. So we use PRP as the base, but we have options. PRP is platelet, platelet rich plasma from your own blood. But we have the option of doing young plasma with the added bonus of all the useful factors, including tons of those exosomes that turn on the mitochondrial energy production. And we can use exosome as well. And then another favorite of mine is adding Botox. So we talk about Botox for the skin, but for a lot of people.

Ben Greenfield [00:33:17]: Will be thinking like, why the heck would you inject a paralytic toxin, right?

Khanh Nguyen [00:33:22]: And you had it done before and you can see the effect. So in this case, Botox act to relax the smooth muscle covering all the blood vessel going to the penis. And meaning you vasodilate the blood vessel, there's more blood coming, right?

Ben Greenfield [00:33:42]: There's just more room for blood to get in because the smooth muscle is relaxed, Right?

Khanh Nguyen [00:33:47]: Okay, Right. And therefore stronger erection, long, longer lasting. And it also the bolt also migrate to the ganglion and it's somehow it's enhanced sensitivity as well.

Ben Greenfield [00:34:05]: You mean like the nerves, the nerve, ganglion it's rusting. Yeah, yeah. Once the numbing cream wears off, you're numbed for this protocol just for guys who are interested or their significant others who are interested in how this goes down. You're actually injecting the shaf, right?

Khanh Nguyen [00:34:22]: We inject the shaft at multiple position and also at the clen penis. And you know, you numb. So it's not a painful procedure. From one to 10, maybe a one max.

Ben Greenfield [00:34:39]: It's just weird pregnancy. My wife was in there watching. She's like, your feet are twitching. Because I'm like anticipating that it's going to hurt and then it doesn't. But yeah, it is a weird sensation. I don't like to watch it, honestly, because it looks like it would really hurt and it doesn't at all.

Khanh Nguyen [00:34:55]: Right.

Ben Greenfield [00:34:55]: Surprisingly, yeah.

Khanh Nguyen [00:34:57]: But we forgot because we also before we did the injection, we did the shock wave. So again, combination, that's like energy shockwave to create multiple tiny injury to turn.

Ben Greenfield [00:35:13]: On, repair breaks up the old blood vessels. Yeah, yeah, yeah. And so for the woman, I mean, we'll get my wife's perspective on this as well. But you're injecting inside, at the G.

Khanh Nguyen [00:35:24]: Spot, around the G spot and also right into the clitoris. And of course. Yeah, yeah. You being numb.

Ben Greenfield [00:35:34]: Right, Right, yeah. The numbing cream is a must.

Khanh Nguyen [00:35:37]: And for women, same thing. By injecting all the biologics, you make the tissue healthier. So there's more lubrication. It's like a tighter sensation and more sensitivity. And so talking about women and men, but for women, like 18 to 40 year old, 35% of women have like sexual dysfunction and then that just go up with age. And for postmenopausal women, it's high. It's like up to 85% of women. Childbirth affect that, like the nurse, childbirth affect that, pelvic floor issues, issues will affect that, you know, for women is relationship, stress, body image, all of that is just a whole bunch of stuff.

Khanh Nguyen [00:36:35]: So, you know, I address everything before we do the O shock. Right. Okay. We have to fix the hormones and look at the medication. Treat any metabolic, any, you know, medical issues like uncontrolled diabetes, high blood pressure, depression, medication, all of that. Hormone replacement is key for men and women. But then when you do all of that and then you do the injection, that's when you see the huge benefit. And it's just really fun for me to see people start to really enjoy sex.

Khanh Nguyen [00:37:09]: And it's healthy for confidence, for relationship, but it's just for your health.

Ben Greenfield [00:37:14]: Yeah.

Khanh Nguyen [00:37:15]: So It's a really. You know, it just sounded very kind of vain or.

Ben Greenfield [00:37:20]: Yeah, it's hard to describe. Like, I've done protocols like this, and yeah, it's just like it. There is more pleasure because the nerve endings seem a lot more sensitized. As a man, you're. You're bigger, you have better blood flow, you last longer.

Khanh Nguyen [00:37:38]: Right.

Ben Greenfield [00:37:38]: And so, yeah, it's. It's pretty interesting to actually. I mean, that's one of those things where. Yeah. I mean, you can go out and test drive it and see how it actually works. Before we go talk with my wife and get her perspective. Another question that I get from people. For both the protocol that we just talked about, the sexual rejuice stuff, and then also the plasma, how often should or do people do this?

Khanh Nguyen [00:38:04]: Yeah. So I really encourage people to be more proactive and think of this like a. Like a health maintenance. You know, do your skin and the P shot or O shot, at least once a year, if possible.

Ben Greenfield [00:38:19]: Okay. So the sexual stuff. Yearly. What about the plasma?

Khanh Nguyen [00:38:22]: Or more, you know, depending on how severe you are, how unhealthy you are.

Ben Greenfield [00:38:26]: Yeah.

Khanh Nguyen [00:38:26]: But at least, like, for healthy people, once a year will be great. You can do, you know, every night, once, six months. Because it doesn't hurt. In terms of young plasma, if you have chronic issues, neurodegenerative condition, we're more aggressive. So we do it, like, even repeat in six months for healthy people, nine months, a year or longer.

Ben Greenfield [00:38:54]: So if you were just in this for, like, the longevity game and want to renew plasma, you could do like an annual basis. Yeah.

Khanh Nguyen [00:39:01]: Right. And again, I love the combination. And actually, I'm not sure if I share with you, but since your last visit, now, there's a thing. It's called the Ben Greenfield protocol.

Ben Greenfield [00:39:13]: Oh, it's on your website.

Khanh Nguyen [00:39:16]: People call and say, I want a Ben Greenfield Protocol. So that's like the young blast Mike. Change the B cell, stem cell, the skin, the P shot.

Ben Greenfield [00:39:26]: Yeah. And you guys do the full meal deal. You can, like, fly into Austin. You've got. We're staying at a house of. Normally, like, you put people up in the hotel, you send a car to the airport. You pick. So basically you have the whole thing as almost like a medical vacation for people.

Khanh Nguyen [00:39:39]: Right. And because, you know it, they do spend a long day here because we try to stack and do as much.

Ben Greenfield [00:39:47]: Like six, seven hours a day. Yeah. And we got a lot in over those three days.

Khanh Nguyen [00:39:51]: Right.

Ben Greenfield [00:39:51]: Yeah.

Khanh Nguyen [00:39:52]: And then I'm really excited. I share with you a little bit I'm adding the TMS and the.

Ben Greenfield [00:39:58]: The transcranial magnetic stem.

Khanh Nguyen [00:40:02]: Yes. For the brain. For the brain. And the brain mapping with that, that's.

Ben Greenfield [00:40:07]: The qeeg, Right, Right. So you're able to test electrical activity in the brain.

Khanh Nguyen [00:40:12]: Right.

Ben Greenfield [00:40:12]: Or brain.

Khanh Nguyen [00:40:13]: And that would guide the TMS treatment. So it's like a better way of doing that. And then that QEEG allow us to track, like, we do it before and then after TMS treatment to see the improvement.

Ben Greenfield [00:40:30]: And tms, would that be primarily used for, like, dementia and Alzheimer's prevention?

Khanh Nguyen [00:40:35]: So it's FDA approved for depression, but now we use it beyond that for cognitive enhancement for autism, for anxiety?

Ben Greenfield [00:40:49]: Yeah. Tim Ferriss has talked a lot about tms, I believe, for depression.

Khanh Nguyen [00:40:53]: Yeah.

Ben Greenfield [00:40:55]: I've never really done it, but is that, like. Is it like a helmet that you wear, or is it.

Khanh Nguyen [00:40:59]: It's mainly like a big coil magnetic, you know, place guided by, you know, what's going on with your brain.

Ben Greenfield [00:41:08]: Okay, so is someone, like, holding this device in your brain?

Khanh Nguyen [00:41:10]: No, it just. It kind of has an arm. We need to position it.

Ben Greenfield [00:41:14]: Just position it up near the head. And how long does the treatment take?

Khanh Nguyen [00:41:18]: Usually it's 15 minutes, 30 minutes. Yeah, yeah.

Ben Greenfield [00:41:21]: And people need. People can't, like, do this at their house, right? They need to do that at clinic.

Khanh Nguyen [00:41:25]: No, this is something that you have to do in house. Yeah, the. The. The neurofeedback system is something that there is a remote device you can do at home.

Ben Greenfield [00:41:35]: Yeah, I've done remote neurofeedback before. Yeah. Yeah. We put, like, the electrodes on your head, and it maps your brain works.

Khanh Nguyen [00:41:41]: It's very cool.

Ben Greenfield [00:41:42]: Yeah.

Khanh Nguyen [00:41:42]: So the combination. I'm really excited. Yeah.

Ben Greenfield [00:41:45]: Cool. Should we go talk to Jessa, see what she's doing? All right, here we go. And before we transition over to Jessa again, all the show notes, you can go to BenGreenfieldLife.com Austinplasma just like it sounds. And there's. We have some great. We had a videographer here the whole time, so we got some videos and photos of this stuff. You guys can see. Don't worry.

Ben Greenfield [00:42:03]: We blurred out the crotch shots. Yeah. Let's go talk to Jessica.

Khanh Nguyen [00:42:07]: Yeah. We have so much fun.

Ben Greenfield [00:42:08]: All right, here we go. Go. So, babe, we were just talking about all of the. The soup of treatments that we did this week and then a lot. I know you did some different things. You're doing the plasma exchange right now, so blood coming out, and then this is going to pull out old plasma. Then you get the albumin back in. But we're all adults here, so we can talk about this.

Ben Greenfield [00:42:34]: You also did the sexual rejuice stuff.

Khanh Nguyen [00:42:36]: Yes.

Ben Greenfield [00:42:37]: What was that process like? Like getting all the injections and stuff?

Jessa Greenfield [00:42:41]: I mean, downstairs, I think it was pretty gentle because everything's numb. They do a good job of numbing. I had the O shot before with no numbing, which was pretty painful.

Khanh Nguyen [00:42:52]: Right.

Jessa Greenfield [00:42:53]: It's brief, but painful. But this was a lot more pleasant in that regard. And, I mean, you feel pressure, but you don't. It's not painful.

Ben Greenfield [00:43:02]: Yeah.

Jessa Greenfield [00:43:03]: So if you're afraid of that being painful, it's really not that bad.

Khanh Nguyen [00:43:07]: Right.

Jessa Greenfield [00:43:08]: I'm not gonna say there's zero discomfort.

Khanh Nguyen [00:43:10]: But there is very valuable.

Ben Greenfield [00:43:12]: Yeah. What do you think about the facial stuff?

Khanh Nguyen [00:43:15]: Oh, but we also did the wings lift that Ben know about.

Ben Greenfield [00:43:20]: Wing Lift. Great name. What's involved with the wing lift?

Jessa Greenfield [00:43:24]: The wing lift is. Well, it's got hyaluronic acid.

Khanh Nguyen [00:43:28]: Right. And then we inject the young plasma and prp. And so that one is just strictly for look, but it's instant and it's, you know, create a fuller appearance of the labia. Yeah, yeah, yeah.

Ben Greenfield [00:43:42]: Okay. You can hop in while we're doing this. Everybody knows we're at a medical facility.

Khanh Nguyen [00:43:47]: Yeah.

Ben Greenfield [00:43:48]: Okay. So the wing lifts is. Sorry.

Khanh Nguyen [00:43:53]: So the shot is to improve sexual function.

Ben Greenfield [00:43:57]: That's the one. That's an actual injection into the spongy.

Khanh Nguyen [00:44:01]: Tissue of the G spot.

Ben Greenfield [00:44:02]: So you go inside.

Khanh Nguyen [00:44:03]: Okay. Tortoise. So that would lead to healthier tissue, leading to more lubrication, tighter feeling, less painful with sexual intercourse, and better sensitivity. The wings lift is just for look, but it's one of my favorite because it's instant, it's natural, it's just, you.

Ben Greenfield [00:44:24]: Know, so that's just like an aesthetic protocol. That would be almost like a facelift for the lady parts, basically.

Khanh Nguyen [00:44:32]: Right. Yeah. And I just have, like, a bunch of women that just really love that. Yeah. Because it's instantaneous. But then most people like, oh, I never looked. And then they. That's what I said.

Jessa Greenfield [00:44:44]: I was like, I honestly haven't compared, so I wouldn't know. Yeah, I didn't know.

Khanh Nguyen [00:44:49]: Right, right. So. But so I explained to people that's just strictly for look. Yeah, yeah. And, you know, you gotta start doing.

Ben Greenfield [00:44:55]: Like, couples packages and.

Khanh Nguyen [00:44:57]: Yeah, actually, we do.

Ben Greenfield [00:44:59]: Oh, you do?

Khanh Nguyen [00:45:00]: But sometime we'll see, you know, the husband or the wife and then. Yeah, yeah.

Ben Greenfield [00:45:07]: Do couples packages.

Khanh Nguyen [00:45:08]: Yeah, right. Yeah, right. It makes sense. Yeah.

Jessa Greenfield [00:45:11]: I do think the wing lifts like the residual, like, I don't want to say pain, but like soreness. Soreness. Yep. That's definitely longer than the osha. The osha. I honestly feel at all.

Khanh Nguyen [00:45:23]: Right. That's true. Yes. Yeah. Cool. Yeah.

Ben Greenfield [00:45:26]: Well, thank you for giving us your perspective.

Khanh Nguyen [00:45:29]: All right.

Ben Greenfield [00:45:29]: I think a lot of women want to hear from you versus me because I don't have a G spot. I don't get a wing lift either.

Khanh Nguyen [00:45:38]: But with the old shot, I want to share, like, my personal experience and this is one of the things that I really love. The added benefit O shot is great for better sexual function, but it's amazing for urinary incontinence. Yeah. So like if you have birth, you know, childbirth, it's annoying. Like when you sneeze or you laugh and you leak, it's no fun. And the first time I had it done and I sneeze and nothing happened, it's like, yeah, that's like the best thing. Yeah. So it's one of my favorite procedures.

Ben Greenfield [00:46:16]: Just in case you sneeze in the future. Cool.

Jessa Greenfield [00:46:19]: I think when I work out, it.

Khanh Nguyen [00:46:20]: Tells me when you hey.

Ben Greenfield [00:46:24]: So BenGreenfieldLife.com Austinplasma check out the Show Notes. I'll link to this stuff. If you want to come on down to Austin region, check this stuff out for yourself. The entire staff here is super friendly. You guys even order in like seed oil free food while we're here and feed us well. And you're really well taken care of down here. So we love what we do. Check it out.

Ben Greenfield [00:46:46]: Leave your questions, your comments, your feedback in the show notes. I read them all. I'd love to hear what you guys think. And thank you for joining for this special episode with Dr. Nguyen at Austin Regen.

Khanh Nguyen [00:46:57]: Thank you.

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