Reading time: 5 minutes
What I Discuss with Mickey Trescott:
- How Hashimoto's disease and celiac left Mickey bedridden at 26, why doctors said her diet had nothing to do with it, and how that drove her to develop the Autoimmune Protocol (AIP), a science-backed elimination diet for reducing inflammation and identifying food triggers….05:59
- Why genetics are only a small piece of the autoimmune puzzle, and what actually triggers onset, from stress and pathogens to vitamin D and A deficiency and traumatic life events…11:38
- Why iodine supplementation can worsen autoimmunity in Hashimoto's and Graves' disease, and how to get what you need from seafood without stoking the autoimmune process…16:48
- What's new in The New Autoimmune Protocol: four pilot trials, a community of 1,000 trained practitioners, and a modified AIP route for people who found the original protocol too restrictive…21:16
- Why AIP is as much about what you add (bone broth, fermented foods, high-fiber plants, and organ meats) as what you remove, and why the most important lever is different for every person…28:15
- A full day of eating on AIP: breakfast patties with sweet potato and chard, a sardine and herb salad for lunch, slow-cooked meat for dinner, and what to do about snacks and smoothies…32:26
- What actually belongs to the nightshade family, why black pepper gets eliminated on core AIP, and why she advises against layering AIP with other dietary protocols like low oxalate…33:22
- Why food sensitivity panels cannot replace elimination and reintroduction, what the Fritscher-Ravens confocal laser studies revealed about reactions appearing up to six days after exposure, and why no IgG test could predict any of it…44:37
- How the 30- to 90-day elimination window works, what measurable improvement actually looks like, how to track your progress for conditions like Hashimoto's where there is no obvious biomarker, and how the reintroduction phase works…53:28
- How to use WHOOP heart rate and HRV data to track food reactions during reintroduction, and why heart rate spikes after an allergen are a well-documented stress response…56:31
- The transition phase: why going from McDonald's to AIP overnight is a bad idea, what a one-month on-ramp looks like, and how to avoid accidentally going low-carb when you are trying to go AIP…58:55
- What modified AIP says about coffee, and why Mickey went seven years without it before coming back to decaf…01:01:42
In this fascinating episode with repeat guest Mickey Trescott, you'll hear how she went from bedridden at 26 with Hashimoto's and celiac disease to overseeing four pilot trials, helping grow a community of 1,000 trained AIP practitioners, and writing the guide to the Autoimmune Protocol, including a new, modified version.
Mickey gets into what a full day of eating looks like, how to handle snacks, smoothies, and seasonings, why food sensitivity panels cannot replace an elimination diet, and how to use wearables like WHOOP to track reintroductions with more precision. We also cover the genetics of autoimmunity, the iodine problem in Hashimoto's, and why three out of four people who follow AIP properly get meaningful clinical improvement.
Mickey is a nutrition professional and one of the founding leaders of the Autoimmune Protocol movement. She wrote the original Autoimmune Protocol, which became the definitive guide to the protocol, and her new book, The New Autoimmune Protocol, is the first official update to it. Based on feedback from thousands of practitioners and millions of patients, plus new research showing many people see results before extensive dietary eliminations, Mickey has added a Modified AIP Elimination route that makes the protocol achievable for more people. Releasing May 26, 2026, the book includes detailed meal plans and 70+ recipes across both the core and modified protocols, covering the full transition, elimination, and reintroduction phases.
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Episode Resources:
People
Products
Books
- The New Autoimmune Protocol by Mickey Trescott
- The Autoimmune Paleo Cookbook by Mickey Trescott
- The Dietary Cure For Acne by Loren Cordain
Podcast Episodes
- What Should I Eat? The Ultimate Podcast GuideTo Choosing The Perfect Diet For You: Part 1
- What Should I Eat? The Ultimate Podcast GuideTo Choosing The Perfect Diet For You: Part 2
Articles & Studies
- Efficacy of the Autoimmune Protocol Diet for Inflammatory Bowel Disease<
- An Autoimmune Protocol Diet Improves Patient-Reported Quality of Life in Inflammatory Bowel Disease
- The Autoimmune Protocol Diet Modifies Intestinal RNA Expression in Inflammatory Bowel Disease
- AIP for IBD: The Gene Expression Study & Patient Experience Survey
- Efficacy of the Autoimmune Protocol Diet as Part of a Multi-disciplinary, Supported Lifestyle Intervention for Hashimoto's Thyroiditis
- Effects of Autoimmune Protocol (AIP) Diet on Changes in Thyroid Parameters in Hashimoto's Disease
- What Is the Efficacy of the Autoimmune Protocol (AIP) Diet in People with Rheumatoid Arthritis? A Mixed-Methods Pilot Intervention Study
- Confocal Endomicroscopy Shows Food-Associated Changes in the Intestinal Mucosa of Patients With Irritable Bowel Syndrome
Do you have questions, thoughts or feedback for Mickey Trescott or me? Leave your comments below and one of us will reply!