Reading time: 7 minutes
What I Discuss with Jimmy St. Louis:
- Trying NAD and Niagen IVs separately at Arete Wellness, what happened when Jimmy stacked them together, and how we partnered to bring that combo to my audience through the Agentis x Boundless protocol…05:48
- The full treatment menu at a modern longevity clinic like Arete, from hormone optimization and peptide stacks to ozone therapy, exosomes, stem cells, and therapeutic plasma exchange…10:07
- How a career spanning cross-country and college and professional football led to three ACL tears, why the third one healed with stem cells and joint injections without surgery, and how his injuries sparked his interest in regenerative medicine…12:28
- Why exosomes are the only biologic treatment Jimmy has tried that produces zero inflammatory response, and what that says about their size and compatibility with the immune system…25:00
- How growing up surrounded by physicians and nurses, combined with his injuries, pushed Jimmy to seek out recovery modalities most athletes never hear about…26:58
- Why so much of the longevity world originated in professional sports, from HRV and red light therapy to PEMF…27:45
- The lifetime benefits the NFL Players Association provides to anyone who ever signed an NFL contract, including tuition reimbursement…30:53
- From four years of CrossFit competitions to finishing third in rowing at the US Olympic trials, and what competing across such different sports taught him about mechanics and efficiency…34:48
- How Agentis Longevity started with a national network of spine surgery clinics performing 100,000 minimally invasive procedures before pivoting into the stem cell space…45:23
- The fragmentation of the longevity industry, and why nobody has defined a standard of care…46:58
- The Longevity Quotient, a battery of five tests that give a single score quantifying how your body is aging relative to your peers, and the custom Agentis x Boundless protocol we built around it…52:03
- Why visceral fat, muscle mass, and phase angle matter more than weight alone, and what phase angle actually measures at the cellular level…55:12
- The FDA-cleared cognition test and why grip strength is one of the most studied proxies for longevity…55:59
- Why cash pay healthcare creates alignment and trust that insurance-based models rarely achieve, and how nutrition fits into the next phase of the care plan…1:01:52
- The Agentis x Ultrahuman partnership, and why being hardware agnostic lets Agentis fold any wearable data into a unified longevity dashboard…1:06:11
In this episode with Jimmy St. Louis, you'll hear how a former NFL player, US Olympic rowing trials competitor, and four-time CrossFit regionals athlete built his career around defining the standard of care in longevity medicine. Jimmy shares the full arc of his path from a three-sport young athlete through three ACL tears, into a spine surgery business that performed 100,000 procedures, and then into Agentis Longevity, a company built around acquiring the best longevity clinics in the country and unifying them under one consistent set of protocols.
You will also get a full breakdown of the Longevity Quotient, the five-test battery Agentis uses to score every new patient, and hear how Jimmy and I built a custom Agentis x Boundless protocol.
Jimmy St. Louis is a healthcare entrepreneur, operator, and former elite athlete dedicated to driving the standard of personalized health, longevity, and regenerative medicine. He is the CEO of Agentis, a platform built to help people live healthier, happier, longer lives through best-in-class longevity treatments.
He also serves as President of the Personalized Health Association, leading a national movement to advance regenerative and personalized healthcare through advocacy, education, and collaboration.
A former NFL player and US Rowing Team member, Jimmy holds a B.S. in Business Administration, an MBA, and dual M.S. degrees in Finance and Telecommunications. He lives in Nashville with his wife Jillian and their three children: Brooke, Phoenix, and Leonidas.
You can learn more about the Agentis x Boundless protocol here.
Agentis x Ben Greenfield Boundless Protocol

If you want to try the Agentis x Ben Greenfield Boundless Protocol mentioned in this show, here's how to get started.
Go to Agentis Longevity’s website to book your LQ assessment. It's a $149 blood panel that measures over 60 biomarkers. Most annual physicals test fewer than twenty biomarkers.
Within five to seven days, you'll get your Longevity Quotient (one number from 0 to 99 that quantifies how your body is aging compared to your peers) plus a full biomarker breakdown and your personalized protocol built by Agentis's clinical team.
Then your first kit ships to your door. You follow a three-stage, twelve-week protocol:
- Foundation (Weeks 1–4): Reset inflammation, rebuild sleep architecture, prime mitochondrial function.
- Optimization (Weeks 5–8): Physician-prescribed interventions layer in where your panel calls for it. Advanced recovery stack. Cognitive protocols.
- Personalization (Weeks 9–12): Lock it into your default operating mode, then retest to see what changed.
You get peptides and supplements matched to your actual bloodwork, video modules walking you through each week, and direct access to clinicians who adjust your protocol as your data evolves.
Choose your path: Your labs can be drawn at home with concierge telemedicine anywhere in the country, or in-clinic at Arete in Nashville with access to sauna, cold plunge, and hyperbaric oxygen.
No commitment to start. HSA/FSA eligible.
Use code AGENTIS15 for 15% off at checkout.
Start your journey with Agentis Longevity here.
Episode Sponsors:
BIOptimizers Magnesium Breakthrough: The seven essential forms of magnesium included in this full-spectrum serving help you relax, unwind, and turn off your active brain after a long and stressful day so you can rest peacefully and wake up feeling refreshed, vibrant, and alert. Go to bioptimizers.com/ben and use code ben15 for 15% off any order.
Pendulum: Metabolic Daily is a powerful multi-strain probiotic that improves your metabolism, reduces sugar cravings, breaks down carbs more efficiently, and sustains your energy levels. You'll receive 20% off your first month of any Pendulum probiotic with code BEN at PendulumLife.com.
Anthros: You can train hard and still undo a lot of that progress by sitting for the next eight hours, which is why Anthros takes a different approach, starting with a Precision Posture System at the pelvis so your spine naturally aligns, plus a built-in Clinical Posture Consult that helps identify issues you may not even realize you have. Go to anthros.com, use code BEN for an exclusive $200 discount, and try it risk-free for 60 days.
Young Goose: To experience the transformative power of Young Goose's cutting-edge skincare products, visit younggoose.com and use code BGF10 at checkout to enjoy a 10% discount on your order.
Episode Resources:
People
Companies
Products & Protocols
- The Longevity Quotient x Boundless Protocol (Use code AGENTIS15 for 15% off)
- Red Light Therapy (use code GREENFIELD for 15% off)
- PEMF
- Tru Niagen
- Ultrahuman
Books
- The Fourth Phase of Water: Beyond Solid, Liquid, and Vapor by Gerald Pollack
Do you have questions, thoughts, or feedback for Jimmy or me? Leave your comments below, and one of us will reply!
One Response
That was the worst podcast you’ve done in awhile. I’m fine with vedors but more health/longevity content.