-Who is Amitay Eshel?…05:25

• Ben met him at a health event dinner 
  • Talked about skin rejuvenation process
• CEO of Young Goose (code GREENFIELD for a 5% discount auto-applied at checkout)
  • The world's first biohacking skincare company
• He was a member of the Israeli special forces
• Geeked out on the Torah

-Why is Amitay’s company called Young Goose?…07:45

• They did their research in the longevity lab of the Weizmann Institute
• Similar to MIT, just in Israel
• The mascot of the lab was a goose
  • Geese reach maturity at 2 years, and then they look the same until they die
• They trademarked the word hormesis for their cosmetics
  • The name was already in use in other fields
• Decided to call the company Young Goose

-Amitay’s thoughts on micro-needling and derma rolling…09:38

• A big proponent of both
• The real issue is balance and homeostasis
• Longevity and optimal performance at the moment
• Microneedling needs supporting repair
• Alitura Microneedle Derma Roller (use code BG20 to save 20%)
• Radiofrequency and microneedling
• Radiofrequency is a way to heat up only the subdermal layers of the skin
• Laser ablation creates damage closer to the surface of the skin
• Brian Johnson’s procedures
  • Demand for immediate repair
  • Nothing to do with longevity
  • Only promoting the appearance of youth
• Podcast with Bryan Johnson:
  • A Step-By-Step Blueprint For Longevity: The Most Advanced Age Reversal Strategies Known To Humankind, With Bryan Johnson.
• There are no long-term skin health impacts of laser use
  • If you do it consistently, you're actually causing more damage than good
  • You are causing repair that your body has never really evolved to deal with
• Every time you ask for cellular turnover in any place in your body, you're increasing senescence as a byproduct
• Increasing oxidative stress as a byproduct which is correlated with aging rather than longevity

-Why is the use of lasers on facial skin so popular?…16:51

• Similar to doping in sport
  • Goal is to look your best right now, in contrast to longevity
• The use of lasers makes skin thinner and less pliable
• The importance of vitamin C and vitamin A
• Avoid ascorbic acid because it’s genotoxic
• Laser can cause long-term frailty of the skin
• Heat in the skin is not the best
• The benefits of red light therapy and green tea – Green Tea Phyto-Serum (code GREENFIELD for a 5% discount auto-applied at checkout)

-The advantages and disadvantages of red light therapy…22:09

• Near-infrared and far-infrared are completely different in the way they interact with the body
  • Near-infrared – low absorption in water
  • Far-infrared – high absorption in water
• What gets transferred into chemical energy doesn't get transformed into thermal energy and vice versa
• Near-infrared – more of a rejuvenating, hydrating, and mitochondrial benefit on the skin level
• Far-infrared – more of the heating – hormetic benefit
• How can we improve that energy production?
• How can we mitigate some of the negative effects of an infrared sauna?
• EGCG, which is the main antioxidant in green tea, is a very precise antioxidant
• A green tea serum for the face before exposing yourself to far infrared light
  • Good at scavenging free radicals
  • Combined with vitamin E and hyaluronic acid
• Green Tea Phyto-Serum – key ingredients are EGCG and hyaluronic acid
• HigherDOSE face mask and neck enhancer
• Ben’s experience with face masks
  • Clay Mask (use code BG20 to save 20%)
• Amitay’s sauna practice
  • Multiple times a day to increase growth hormone
  • Exposes very specific areas to infrared

-How to protect the skin from sun exposure…34:09

• The Skinny Confidential's Get the F*ck Out of the Sun by Lauren Evarts Bosstick
• Avoiding the sun vs. seeking the sun
• Recent podcast with Dr. Joe Mercola:
  • Staying Fit With Sunshine & Blood Flow Restriction, The Superiority Of Goose Eggs, The Latest On EMF Protection, Is Vegetable Oil The Root Cause Of Most Modern Diseases? With Dr. Joe Mercola.
• The most benefit you can get from the sun is on your torso and your belly button area
• You are damaging DNA when you're exposed to UV and artificial blue light
• Use zinc oxide-based sunblock if you want to prevent sun damage to the skin
• Bio-Shield SPF40 (code GREENFIELD for a 5% discount auto-applied at checkout)
  • Apply before sun exposure or before traveling to protect from pollution, blue light and EMF
  • Uses non-nano zinc oxide, micronized zinc oxide
  • Ectoin natural – an amino acid 
    • Took about four years to develop
    • Protects proteins from environmental damage, from oxidation, from EMF, pollution, and heavy metals
    • Powerful antioxidant similar to C60
  • Ectoine peptide – a natural extremolyte, found in Bio-Shield, is a powerful protector against environmental stressors like UV radiation EMF and pollution.
  • Ectoine helps maintain the skin's moisture, stabilize cell membranes, and stimulate the skin's repair mechanisms.
  • This results in resilient, glowing skin

-The benefits of Bio-Barrier Serum…40:46

• Leaky skin 
• The better your skin microbiome and skin barrier function, the more you're promoting longevity in the skin
• People in the Western world age the most from environmental aggressors
• Bio-Barrier has biomimetic lipids (code GREENFIELD for a 5% discount auto-applied at checkout)
• Every skincare product has something that's called vectoring
  • Ingredients have to be of the right size for the skin to absorb them
• Bio-Barrier is best absorbed on the skin
• Serums are best to be absorbed deeper into the skin
• More than just an active ingredient is needed
  • It also needs to be vectored or placed in the right place to be absorbed correctly

-NAD research and products with NAD…45:43

• NAD as a molecule has two challenges
  • It's about 50 times bigger than your pores, so it's not going to absorb
  • Your skin doesn't know what to do with it
• You can take it orally, inject it, or get an IV
• Or it can be broken down into its precursors – to its building blocks
• The same is true with collagen
• Seven-year study to create products with NAD
• For proper DNA repair, NAD, when taken orally, needs to be combined with sirtuins like resveratrol or pterostilbene.
• C.A.R.E. NAD+ Boosting Moisturizer
  • Enhanced Fermented Resveratrol – patented process increases its bioavailability 50 times, the skin truly benefits from the SIRT1 activation offered by resveratrol. This is an ingredient in the CARE Moisturizer.
  • Sirtuin activators used
    • Fermented resveratrol
    • Tiliroside from strawberry
  • Matrixyl 3000 Peptide is also used in our CARE Moisturizer – works as a messenger, initiating the collagen repair process leading to smoother, firmer skin.
  • Astragaloside IV in the CARE Moisturizer has the ability to activate telomerase, which could increase the lifespan of skin cells, and is a mild senolytic
• Qualia 
• The problem with resveratrol is that it is a stressor
• NAD+ Nobel – A liposomal, nano-sized, patented blend of NAD+ precursors, NR and NMN, is incorporated in the C.A.R.E. and EyeC.A.R.E. eye cream. Designed to enhance NAD+ levels in skin cells
• SNAP-8 Peptide in the EyeC.A.R.E. is a softer alternative to Botox, works by inhibiting neural activity, reducing muscle contractions, and potentially preventing wrinkle formation

-Is ascorbic acid genotoxic?…49:59

• Ascorbate is great; the problem is ascorbic acid
• What are the subtle differences between whole-food vitamin C and ascorbic acid?
  • Ascorbic acid is synthetic
• The average skincare product is sitting on the shelf for about 18 months
• Ascorbic acid is extremely reactive and volatile
  • It excites iron molecule molecules in the skin which causes DNA damage
  • The most toxic common skin ingredient
• The safest is calcium ascorbate
• A water-soluble version that is very good is called MAP (Magnesium Ascorbyl Phosphate)
  • Very difficult to get high amounts in skincare
• Calcium Ascorbate is used in the C.A.R.E. product
• ProC.A.R.E., the senolytic serum uses THD ascorbate
  • THD is six times stronger or more impactful than ascorbic acid
• Is there any proof that spermidine is effective on skin?
  • Research tied to The University of Graz in Austria
  • It has effects on the skin thickening of the dermis

-The proper order to use different skincare products…54:18

• How to use the different skin care products:
  • Wash your face with the Adaptogenic Cleanser
  • Apply ProC.A.R.E.
  • Apply EyeC.A.R.E. under the eyes and around the orbital bone
  • Apply C.A.R.E. on face, neck, and chest
  • In the PM: Apply the Hyperbaric Mask over other products on under eye, face, neck, and chest and leave it overnight (every night for the first four weeks and then 2-7 times per week).
• Ben’s experience with skincare
• Need to clean your face first
  • Need something that can that can basically bind to oils
  • And just remove the oils from the surface of the skin
  • Also want to eliminate a molecule called CD38
  • And heavy metals or pollutants that have been attached to outer layers of the skin
• The cleanser can be used as shaving lubricant
• Gua Sha
• The benefits of Gua Sha
  • Massaging your face with a contoured stone
  • Mostly for lymphatic drainage

-Is Botox bad?…1:00:45

• Botox is paralyzing the muscles in the face
• A University of Southern California USC study in 2011
  • Showed that micro-expressions in the face are important for mirroring and mimicry
• UC Irvine released another study this year 2023
• We subconsciously micro-mimic other people’s emotions to understand them
  • Botox inhibits that function
• On the other hand, Botox can relieve some anxiety and depression for the same reason

-The social impact of skincare…1:02:33

• Many studies show that there is a correlation between the way you look and the ability to influence people
• Study was published in the British Medical Journal in 2009 on perceiving someone’s age
• AI with facial photography can be a better diagnostic tool than bloodwork
• Facial apps to determine stress, biological age, etc.
• AI has problems determining skin health with photography because of light discrepancies

-Skincare routine after cleanser…1:06:54

• Bio-C Peptide Spray (code GREENFIELD for a 5% discount auto-applied at checkout)
• Beam Minerals spray
  • Not mandatory because your pH is usually balanced
  • Allows other ingredients to penetrate correctly
• Podcast with Caroline Alan:
  • Fringe Minerals From Dirt & Why You Need Them: The Full Story Behind Fulvic & Humic Acid, With BEAM Mineral’s Caroline Alan.
• Amplifying Essence
  • The first treatment
  • It can be bypassed
• Next is the Serum
  • The richest and most active ingredients
  • Absorbs the most into the skin
• Customized serums
  • ProC.A.R.E. Senolytic Serum
    • Eliminates senescence cells
    • Mimics things like rapamycin and metformin
    • Very potent type of vitamin C
    • To be used in the morning
    • Matrigenics 14 G in the ProC.A.R.E. Senolytic Serum is a patented microalgae extract that reactivates 14 genes to restructure the skin's extra-cellular matrix, promoting a youthful appearance.
    • Juvenessence is a patented senolytic algae extract in the ProC.A.R.E. Senolytic Serum – slows down skin aging by downregulating mTOR and the skin aging protein Progerin
  • Bio-Retinol Serum
    • Retinol-based serum
    • It mimics how your body expresses vitamin A
    • To be used in the evening
  • Bio-Barrier Serum – apply after micro needling or before physical activity in the cold. Repairs and protects skin barrier
    • Barrier skin repair serum
    • To be used in the evening
  • Green Tea Phyto Serum – apply 2-3 minutes before red light therapy to double the benefits on the skin
  • C.A.R.E. NAD+ Boosting Moisturizer
    • Care and boosting moisturizer
    • Very slow release of ingredients
    • NAD precursors, fermented resveratrol, peptides
  • Hyperbaric Mask (code GREENFIELD for a 5% discount auto-applied at checkout)
    • Number one seller
    • It mimics the rejuvenating effect of being in a hyperbaric chamber
    • Improves energy production in the mitochondria
    • Vitacell LS 7979 in the Hyperbaric Mask is a natural probiotic, a robust activator of bioenergetic metabolism and ATP production in skin cells. It enhances and mimics the skin rejuvenating effects of HBOT.
    • TEGO PEP-UP 4 Peptide is a pro-peptide in the Hyperbaric Mask – upregulates genes responsible for collagen production leading to stronger, firmer skin.

-Amitay’s thoughts on Wim Hof and cold thermogenesis…1:17:07

• When you subject yourself to the raw natural energy of rejuvenation, you need to strip away the negative effects of it
• The function of skin after reproductive age
• When taking a cold bath, it’s better to leave face out of the water
• Teamwork in Special Operations Unit
• Most of the Special Forces veterans in Israel go into the tech industry
• Amitay ended up in a red light therapy company
• Later invested his money into NAD research
• His wife Anastasia is renowned biologist and biohacker
• Biohacking Beauty podcast
• Young Goose (code GREENFIELD for a 5% discount auto-applied at checkout)

-And much more…

Upcoming Events:

• Couples Collective: October 25th – 29th, 2023

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Click here for the full written transcript of this podcast episode.

Resources from this episode:

– Amitay Eshel:

• Young Goose (code GREENFIELD for a 5% discount auto-applied at checkout)
  • Bio-Shield SPF40 Environmental Protection
  • Bio-Barrier Serum
  • C.A.R.E. NAD+ Boosting Moisturizer
  • ProC.A.R.E. Senolytic Anti-Aging Serum
  • Bio-C Peptide Spray
  • Amplifying Essence
  • Bio-Retinol Wrinkle and Skin Tone Correcting Serum
  • Hyperbaric Mask
• Biohacking Beauty Podcast

– Podcasts:

• A Step-By-Step Blueprint For Longevity: The Most Advanced Age Reversal Strategies Known To Humankind, With Bryan Johnson.
• Staying Fit With Sunshine & Blood Flow Restriction, The Superiority Of Goose Eggs, The Latest On EMF Protection, Is Vegetable Oil The Root Cause Of Most Modern Diseases? With Dr. Joe Mercola.
• Fringe Minerals From Dirt & Why You Need Them: The Full Story Behind Fulvic & Humic Acid, With BEAM Mineral’s Caroline Alan.

– Other Resources:

• The Skinny Confidential's Get the F*ck Out of the Sun by Lauren Evarts Bosstick
• Joovv Red Light
• HigherDOSE
• Alitura Microneedle Derma Roller (use code BG20 to save 20%)
• Alitura Clay Mask (use code BG20 to save 20%)
• C60 (use code BEN10 to save 10%)
• Qualia 
• Gua Sha
• Beam Minerals

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Do you have questions, thoughts, or feedback for Amitay or me? Leave your comments below, and one of us will reply!