November 7, 2016
“Every man desires to live long,” wrote Jonathan Swift, “but no man would be old.”
What exactly does this mean?
It means that one potent and innate human desire is to live a long time. And I don't know about you, but I don't just want to live a long and full life – I also want to feel really dang good doing it, especially when I'm old. I don't want to be cold, hungry, feeble, frail and fragile. I'd rather be like the impressive, muscular, vibrant seniors I talk about in my article “5 Anti-Aging Secrets From Five Of The Fittest Old People On The Face Of The Planet”.
Yeah, I want to be the ripped ninety year old sprinting down the golf course, loaded down with clubs, basking in the sunshine with a huge smile on my face…
…and hurrying to finish my game so I can get home to pump iron and make love to my wife.
There, I said it.
This is why, a few weeks ago, I published the article “Should You Use This Controversial Hormone Marketed As A Natural “Fountain Of Youth”?” in which I explained how natural compounds such as colostrum, whey protein and the milk of mammals such as cows and goats and camels can be safe and efficacious way to get all the anti-aging, anabolic, recovery, sleep-enhancing, muscle repair and fat loss benefits of elevated growth hormone and elevated insulin-like growth factor (IGF-1) levels. Or, you could be like the world's oldest woman at 116 years old and just eat eggs and cookies every day.
But since publishing that Fountain Of Youth post last week, I've received many, many inquiries from athletes, anti-aging enthusiasts and biohackers who, despite being aware of these”natural” methods such as colostrum, whey and milk, are still extremely interested in the concept of biohacking growth hormone levels and the subsequent anti-aging effect via “better-living-through-science” methods such as injections, stacks and supplements.
And so, in today's article, I'm going to give you everything you need to know about how to use what is probably the most potent of these methods: IGF injections. I'll also fill you in on two types of compounds that should accompany any IGF injections – Growth Hormone Releasing Peptide (GHRP) and Growth Hormone Releasing Hormone (GHRH).
I am not a doctor and this is not to be taken, interpreted or construed as medical advice. Please talk with a licensed medical professional about this. These are just my own personal thoughts and not a prescription or a diagnosis or any form of health care whatsoever. In addition, most of this stuff is banned by the World Anti-Doping Association (WADA), US Anti-Doping Association (USADA) and other international governing bodies of sport, so you should not use any of these compounds if you are competing in any sanctioned sport.
Cool? Alright, let's do this.
Why Take Growth Hormone?
In my previous article on growth hormones and IGF, I delved into the nitty-gritty of what exactly growth hormone and IGF are, and why you'd want to elevate them (in moderation) in the first place. The fact is, the amount of growth hormone that your body produces naturally declines as you age and the amount of growth hormone that you need increases based on your level of activity and how much recovery you need and how much you are beating your body up on a day-to-day basis.
Inadequate growth hormone – especially when combined with aging and physical activity – results in muscle loss, decreased elasticity, joint pain, fat gain, decreased stamina and all the other annoying variables we often associate growing old. This is probably why, as people are living longer, wanting to get bigger, stronger, sexier and faster with age, and wanting to stay active and robust much later in life, there is a growing interest in using “better living through science”, including supplementation and injections, to maximize growth hormone levels.
Bodybuilders are a perfect example of a population that – through self-experimentation and guinea-pigging, exchanging practical experiences in threads upon threads of deep “broscience” conversation in forums, and displaying an extreme willingness to push the limits – have learned how to tweak, how to pulse and how to increase growth hormone levels. This is partially because they have to maximize every last drop of training and recovery, day in and day out, and also because they are complete, geeked-out devotees of topics like how to build muscle, lose fat, and shape a physique that (whether or not you think a bodybuilder's body is an “attractive” physique) speaks volumes to their ability to be able to mold the human machine beyond what most folks are able to achieve, and more specifically to be able to intelligently use synthetic hormones and derivatives that help increase muscle recovery, repair joint damage, rejuvenate collagen production, and aid in cellular repair.
Three specific growth hormones that the bodybuilding world was one of the first to tap into, and that are now being explored by the anti-aging, athlete and biohacking communities, are the peptide compounds IGF-LR3, GHRP, and GHRH. Let's delve into what exactly these peptides are and how they can work together to push you past that plateau and into peak shape. If you need a review of what a peptide is, then I'd highly recommend you read my previous articles “How To Use BPC-157” and “How To Use TB-500“.
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What is IGF-LR3?
IGF-LR3 is short for “Insulin-like Growth Factor – 1 Long Arg3”. IGF-LR3 is just a protein, and more specifically a polypeptide hormone that, since it contains some of the same molecular structure as insulin, closely mimics the anabolic effects of insulin. It contains a sequence of 83 amino acids, and the arg3 in the name refers to arginine being in the third position in this amino acid sequence. Should you be curious as to what the amino acid sequence is of IGF-LR3, it is: MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA (I really don’t know why anyone would care about that, but nonetheless, there it is, in all it’s glory for you peptide freaks).
IGF-LR3 responds to signals from growth hormone (GH), and it is the most potent growth factors in the human body, which is probably why it is often referred to in the bodybuilding community as an “anabolic powerhouse”. In other words, this is the stuff that helps you to maintain lean tissue and helps your muscles grow by causing the splitting and forming of new muscle cells (hyperplasia).
While the most well-known property of IGF-LR3 is this muscle maintenance and building effect that helps many folks look better than their built-in genetics intended, there are several other benefits of IGF-LR3, including:
- Increased muscle retention
- Increased physical performance
- Faster recovery
- Increased drive
- Increased effectiveness of the anabolic cycle
- Rapid fat loss
- Decreased effects of aging
- Improved testicular health
- More rapid sleep onset and body recovery during sleep
Bodybuilders first started using this stuff when they found themselves spending hours in the gym each week, eating plain chicken piled on broccoli (with no salad dressing of course), only to find themselves unable to get that extra little bit of fat loss or muscle gain. In other words, IGF-LR3 was originally used as a way to break through a fat loss or muscle gain plateau, with the idea that one could spend weeks at the same weight and fitness level without the use of exogenous IGF-LR3 supplementation, but if a cycle of IGF-LR3 was added, the body suddenly gets sparked into anabolic action again.
From a muscle gain or fat loss standpoint, it's really only the top small percentage of seriously competitive bodybuilders and highly competitive athletes who would get any additional gains from adding IGF-LR3. So it’s probably not necessary for the weekend warriors, the overweight post-New Year’s gym enthusiasts, or the average athlete – unless they are looking for a fast shortcut.
In this case, IGF-LR3 is going to help you get past your physical limitations, but this synthetic protein can have some serious side effects when not used properly, including intestinal, heart, and spleen growth. Very advanced bodybuilders are meticulous and know what they are doing and are able to minimize or eliminate any negative effects by using the strategies you're going to discover in the rest of this article.
So what I’m saying to you is – while the potentially negative risks are minimal when you use the stuff properly and include the type of GHRP's and GHRH's you're about to discover – the risks of simply injecting IGF willy-nilly are very, very real and you don’t want to pretend they don’t exist or just inject random compounds without using proper stacking and combination methods with GHRP and GHRH.
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What Are GHRP's?
As you've just learned, you can't just use IGF all by its lonesome self. To get the most benefit out of IGF, or any other Growth Hormone precursor, you must be familiar with GHRH's and GHRP's.
This is because when you combine these compounds with a peptide like IGF, they cause and amplify a natural pulse of Growth Hormone (GH) from your body. In a nutshell, GHRP's release a pulse of GH, and then the GHRH's release and amplify this pulse. Combining both GHRP and GHRH together, along with a peptide like IGF, can give more than double the effect of either alone. They pack a potent one-two punch when you take them together in a peptide stack. Using both together, and in a cycle with IGF-LR3, stimulates the most growth hormone production and maximizes muscles gains, fat loss, recovery and the other benefits of using peptides like this.
GHRP is short for “Growth Hormone Releasing Peptide”, and is a chemical class of growth hormones in the category of drugs known as GH Secretagogues that stimulate the body's natural release of the natural growth hormone (GH), primarily by stimulating the pituitary gland to produce more Growth Hormone. GHRP's are (as their name obviously implies) peptides, specifically synthetic oligopeptides. There are many peptides in the GHRP family but the four most common are GHRP-6, GHRP-2, Ipamorelin, and Hexarelin – and these are the only ones I'm going to mention in this article, so let’s get to it.
All four of these GHRP's share these common benefits:
- Decrease in body fat
- Increase in lean mass
- Increase in collagen production
- Increase in restorative sleep
- Increased in cellular repair
GHRP-6 is one of the first GHRP's synthesized, and is widely considered to be the most effective of the growth hormone releasing peptides. There's some controversy about that as some people prefer or report superior results with GHRP-2, which is often referred to as the “second generation” version of GHRP's, but the choice between GHRP-6 and GHRP-2 really depends on the outcome you are looking for. You’re going to see benefits from either one.
For example, compared to GHRP-2, GHRP-6 tends to cause a huge increase in hunger. So if you are trying to gain lean mass and muscle, stay very anabolic or are struggling to eat enough food to meet high calorie intake needs based on activity levels, then it make senses to go with GHRP-6. On the flipside, if caloric restriction and rapid fat loss are your goals, then GHRP-2 is going to be a superior choice compared to GHRP-6. GHRP-2 does indeed cause far less appetite stimulation, so it can be a more beneficial choice for someone trying to keep lean and keep their eating in check. If you tend to overeat and struggle with a little excess fat around your middle for example, go with the GHRP-2 instead of GHRP-6. GHRP-2 is often considered superior to GHRP-6 because it can be dosed in higher amounts with less desensitization. Both GHRP-2 and GHRP-6 tend to cause fluctuations in the body's natural production of prolactin and cortisol, which can also be concerning from a hormonal standpoint.
Ipamorelin (IPA) is also a synthetic peptide product that tends to be used solely for growth hormone (GH) release. It can be dosed higher than GHRP-6 or GHRP-2, it has no effect on appetite nor on prolactin or cortisol, and is, in my opinion, the safest of the GHRP's.
Finally, Hexarelin is the most potent of the GHRP's, and is used to significantly bump GH release when combined with IGF. While it's less desirable for long term use as it has a high rate of desensitization, resulting long-term in a need for higher and higher amounts, it can be paired in lower doses with the other GHRP's for more gains. If you’re doing a short cycle of peptides and GHRP's, you can give Hexarelin a try – but I'd stay away from long term use.
When used in excessive quantities or excessive frequencies, or stacked incorrectly with the other compounds you'll learn about in this article, all GHRP's also share a few common negative side effects: specifically water retention, excessive sleepiness, tightness or carpel tunnel-like symptoms in the wrist/hand, numbness and tingling in the extremities, and a decrease in insulin sensitivity.
This is why GHRP-6 should be administered on an empty stomach (no food should be consumed for 15-20 minutes post-injection if maximum GH release is desired. In addition when using GHRP-6 for GH release, the average dosing range is between 100-150 mcg per injection and dosing frequency is between 1-4X per day. In order to get maximal elevations in GH, GHRP-6 should be combined with a GHRH, which you'll learn more about shortly.
Ultimately, to maximize the effects of IGF, you should accompany any IGF use with a GHRP, and from what I've personally researched, the GHRP Ipamorelin appears to be the safest and most efficacious. Like the other GHRP's, its primary function is to stimulate your pituitary gland to produce more growth hormone, and also like the other GHRPs, it has a two-fold mechanism of action, meaning that it causes an increase in GH through amplifying the natural growth hormone releasing hormone signal pathway, and also by suppressing the actions of somatostatin, which can lower growth hormone as you sleep.
Compared to Ipamorelin, GHRP-6 is inferior in that it activates a wider array of potentially undesirable effects beyond GH release, such as intense hunger and gastric motility, as well as inducing a mild effect on cortisol and prolactin. GHRP-2 is slightly less “sloppy” with a more intense GH release, and with less gastric motility and less hunger effect. Hexarelin gives a higher GH pulse, but induces some gastric motility and produces almost zero issues with hunger, although it requires a lot of cycling to avoid desensitization to it's effects.
Ipamorelin is the best choice. Sure: it doesn't release as much GH as the others, but it causes virtually no hunger or gastric motility, does not effect cortisol or prolactin and seems to be the safest choice (although it is the most spendy of the options).
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What Are GHRH's?
GHRH stands for “Growth Hormone Releasing Hormone”, which admittedly seems like a mouthful of double talk, and in a way, it is. It's literally a hormone (an amino acid peptide produced in the hypothalamus) that causes the release of another hormone. GHRH also stimulates any GHRP to increase the release of GH, and in addition, seems to have a significant positive effect on cognitive health.
The main form of synthetic GHRH that one would inject along with GH and GHRP is something called Mod GRF 1-29 (sometimes still referred to by its old name as “CJC1295 without DAC”). The other most common type of GHRH is called “CJC1295Dac”, which I really don't recommend because can only be used for four to five weeks at a time if you want to avoid permanent damage to your pituitary gland. In almost all instances, Mod GRF 1-29 should be used in favor over CJC1295Dac.
In a nutshell, the main reason to use this a GHRH in conjunction with GHRP and GH is to cause an even greater increase in GH than you'd get if you used GH by itself, and also to minimize the negative side effects of using GH by itself. Remember what you learned earlier: GHRP's release a pulse of GH, and then the GHRH's release and amplify this pulse.
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How to Stack & Dose The Ultimate Growth Hormone Peptide Stack: IGF-LR3, GHRH & GHRP
OK, so now that you know all about GH, GHRP and GHRH, let's delve into exactly how you would “stack” these compounds. The best results from any peptides, especially those designed for growth hormone and taken to improve anabolism, fat loss, physique or overall health, are to combine specific combinations of peptides all at the same time. Sure, you would get some improvement by using one peptide at a time, but stacking these things is really where it’s at when it comes to experiencing significant gains in a short period of time.
One of the most popular and reportedly efficacious peptide stacks for improving overall body appearance, losing fat, and gaining muscle in away that does not harm the pituitary gland or shut down your own natural production of Growth Hormone is a combination of IGF-1 LR3 (the GH) ,Mod GRF 1-29 (the GHRH), and Ipamorelin (the GHRP).
Here's how it works:
Like any supplement, vitamin, or medication, each peptide has its own unique dosage instructions. Typically, you’ll purchase a month's worth or “cycle's” worth of the peptide in powdered form in a vial, “reconstitute” the peptide substance with the right amount of sterilized or bacteriostatic water, and then administer it via insulin syringe injection. If you have no clue how to reconstitute a powder with sterilized or bacteriostatic water, then simply click here to read my article on BCP-157, in which I spell it out in great detail, and include links to helpful calculators that tell you exactly how much water to use based on the size of the powder vial you have.
When the powdered form of your peptide is reconstituted, it will then be a liquid, and this liquid must be saved in a dark area, undisturbed except for when you are withdrawing some of the solution into the syringe for use, and preferably kept in the refrigerator or freezer in order to maintain the quality and effectiveness long term. Peptides are extremely fragile, and you have to take extra care of them or they just won’t perform the way they’re supposed to. So even if they're in the refrigerator, try to keep them on or near or wrapped in bubble wrap, and in a place where someone won't, say, knock them around while reaching for the milk.
IGF-1 LR3 can be taken every day of the week for about four weeks before your body becomes desensitized to the stuff and it loses its effectiveness. A good starting dose is 50mcg per day, but you can gradually increase this to 150mcg a day if you’re feel fine with none of the side effects listed earlier in this article (and if you do experience excessive tiredness, just do your injections prior to bed). IGF-1 LR3 gets injected directly into the muscle, or can be injected subcutaneously. And don’t be a baby – it only stings for a minute.
Do not take more than 150mcg of IGF-1 LR3 per day for four weeks, as high doses of IGF-1 have been shown to cause some pretty extreme hypoglycemia and blood sugar dysregulation. In some studies, IGF-1 increased tumor size in patients who already had cancer, but IGF-1 regulates the functioning of our heart, nervous system, and brain cells – so it does not seem to be the cause of cancer or contribute to something like tumor growth unless cancer already exists. So if you already have cancer, the results of these studies would lead me to stay away from IGF-1. Otherwise, I'm not concerned.
The next component of the stack is Ipamorelin. This one is most often injected by subcutaneous injection using an insulin syringe. The average dose of Ipamorelin is 200-300mcg, taken at two to three times per day. Most athletes and weightlifters take an Ipamorelin dose about forty minutes before a workout to get the best workout results, as it is going to kick in and help you power through a high-intensity workout such as weight training or high intensity cardio. Although you can also simply use Ipamorelin before bed along with IGF-LR3 and Mod-GRF, if you take it before workouts it will give you exactly what you need to do to push past those pesky plateaus and get the look you’re trying to achieve.
You can take Ipamorelin for twelve week cycles before it becomes ineffective or the risks for side effects increase. If you experience prolactin dysregulation or any signs of estrogen dominance when taking Ipamorelin, you can take aromatase inhibitors such as Aromasin or Letrozole along with an anti-prolactin aid like Cabergoline to reduce prolactin and symptoms from increases in estrogen. This should keep everything in balance so you can continue using Ipamorelin for the twelve week cycle, and will keep you from getting man boobs and excessively weepy during chick flicks. As you can imagine, this gets pretty complicated, this can get pretty complicated, so I recommend taking the lower doses of Ipamorelin and not ever taking it for more than twelve weeks. This is also important because high doses Ipamorelin taken for over twelve weeks can also cause an increase in cortisol.
But don't get too scared. As I mentioned earlier, out of of all of the GHRP options out there, Ipamorelin is the mildest peptide available for targeting growth hormone (GH) release. It’s safer than some of other GHRP options because it doesn’t significantly affect important natural hormone levels such as FSH, TSH, PRL, or LH blood serum plasma levels the way GHRP-2 or GHRP-6 will.
To complete your peptide stack, you'll need a GHRP, and the top peptide I recommend for this is Mod GRF 1-29. The use of a GHRP like this allows you to increase your body’s own production of growth hormone without taking excessive exogenous injected growth hormone. Mod GRF 1-29 is specifically known to help increase fat loss and increase muscle growth, improve the appearance of connective tissue and skin, and help you recover from injuries and workouts more quickly.
It's also important to know that don’t have to cycle your use of Mod GRF 1-29, which means you can match your usage to your cycles of IGF-1 LR3 and GHRH, or you can use Mod GRF 1-29 all on it's own whenever you need to slightly increase growth hormone levels in your body, such as during a mass gain phase or when you are injured. However, to maintain sensitization, if you are going to use Mod GRF 1-29 on an ongoing basis then make sure you are using the lower end of the recommended dose range, or taking the full-strength dosage just once per day right before you go to bed.
Mod GRF 1-29 is typically injected subcutaneously, intravenously, or intramuscularly, and it seems to be efficacious when administered in any of these ways. If you get a little nervous with needles or dislike experiencing too many injections per day or feel like a freaking pincushion, you can simply add multiple peptide solutions from your peptide stack to the same syringe to reduce the number of injections you need to do each day.
To get the maximum effect, you can inject a dose of 100 mcg of Mod GRF three times per day about thirty minutes before a meal (when insulin and blood sugar tends to be lowest), and incorporate it in a cycle along with the other peptides in this article for four to twelve weeks. If you’re simply going to use Mod GRF 1-29 on an ongoing, everyday basis, throughout the year in the absence of the other peptides in this article, then just take 100 mcg once per day, preferably right before you go to bed.
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Summary: How to Naturally Increase Growth Hormone & Where to Buy Peptides
OK, OK, I get it: some people want to get the results without injecting themselves with peptides. Some people can't legally inject peptides. Needles and injections and synthetic hormones don’t sit well with everyone.
This is why, in the past, I’ve provided you with a number of articles about how to naturally increase growth hormone levels, including the most recent article I wrote about natural ways to increase IGF-1, whic includes tips such as including more quality sleep, decreasing alcohol consumption, increasing dairy consumption, using natural supplements such as colostrum and whey protein, sprinting and weight training.
Ultimately, you don't have to sit back and let father time slowly peck away at you. If it's legal, safe and efficacious, I'm a fan of better living through science, and the stack you've just discovered is one of the most potent ways to pull this off. ou'll reduce your risk of many chronic illnesses, enhance your vigor and enjoyment of life, slightly slow the tick of the aging clock and perhaps more importantly, be stronger, sexier and more vigorous as you age.
If you do want to try a peptide stack, then you may be wondering where you’re supposed to get these mysterious substances. You can't just waltz into your local Walgreen's or GNC and buy them, nor can you find them on Amazon. They’re only sold from US suppliers for research purposes. If you want to know if what you're getting is effective, just take a look at the bottom of the little glass bottle when it gets to you. The powder “puck” should be tight, packed and uniform, not clumped or broken. As you've learned, you still need to be quite careful when you reconstitute the powder, but this doesn't matter if what you're getting isn't synthesized properly or isn't handled carefully during shipping, so choose your source wisely.
Here's the skinny on pricing and quantity:
Ipamorelin: 5mg typically runs about $46. Depending on your frequency of cycling and dosage, that will last you about three to six weeks. So for a full twelve week cycle, get three to four bottles.
Mod GRF 1-29: 2mg runs about $33, and will last for a similar period of time. I'd recommend three to four bottles.
IGF-1 LR3: 1mg sells for about $98, and will last for a similar period of time. Same as above: three to four bottles.
Do you have questions, thoughts or feedback about growth hormones, growth hormone precursors, growth hormone injections or anything else from this article? Share what’s working for you and what isn’t. Leave your comments and feedback and questions below.
Can IGF-1 LR3 be stacked successfully with Frag 176-191? Any help would be greatly appreciated.
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Can you please share your thoughts, experience and information on Omnitrope…and whether it can or should be combined with BPC157 or TB500? Ty!
hi iv been taking 5iu aday Monday to Friday for last 5mths can I take ghrp 2 and ghrp 6 together with hgh or just take 1 of them ? I’m also about to start a course of anavar test and then please advise thank you
I bought everything & am following all of Ben’s instructions. Are there no blogs someone could refer me to or forums where people talk about this stuff?
$32 for 5mg of ipamorelin?? How and where??
Hi Ben..I am a 49yr old female and I’m wanting fast fat loss. I build muscle very fast but I’m 5’4… I’m considering a cjc1295 no dac 5 mg with Ipamorelin 5mg Blend or is it better to go with the Tesamorelin? And how much per day? I’m 150 pounds trying to cut 25 pounds off.
Can I stack the cjc1295/ipamorelin blend with the Tesamorelin?
@trainwithvivek he is genius ask him he can help
Hi.
I have been using CJC-1295 with ipamorelin blend. I do it 5 days on 2 off.
I am in my 50’s. I am
At the gym 3-6 times per week. Most weeks 5 days. It works great. You will see it hit about week 6.
Obviously work out n eat right.
These articles are completely worthless without publish dates. If you go back and just start reading articles on this website, you’ll see that Greenfield contradicts himself all over the place. That’s to be expected to a degree as knowledge and science evolve, but you can’t identify the chronology or tell what’s current and what old here.
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Hi Ben,
I’m a little confused. In this article you link your original “Fountain of Youth” article where you call out:
“I don’t recommend growth hormone stacks like IGF-1, GHRH’s, GHRP’s or any of the like. As you’ve just discovered, the risks and unknowns are just too great.
Plus, this stuff is banned by just about every international sporting body.“
But then a few weeks later you published this article, giving direct recommendations on stacks.
Which is it?
Trying to do my own research and these articles were super informative, but your opposing stances confused me.
Thanks
Is there a way to see the date of your article publications? I’m curious to be able to track the info in conjunction with your own continued evolution and learning. I find some articles that are “out-dated” compared to your latest understanding of topics.
Also, this article is a near mirror of the Functionised article on the same topic here:
https://functionised.com/podcast/how-to-use-growth-hormone-peptide-stacks-for-a-better-body-and-a-better-you-with-jim-goetz
Which came first?
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Hi Ben..I am a 44yr old female and I’m wanting fast fat loss. I build muscle very fast but I’m 5’3… I’m considering a cjc1295 no dac 5 mg with Ipamorelin 5mg Blend or is it better to go with the cjc1295 no dac 2 mg and ipamorelin 2mg blend? And how much per day? I’m 150 pounds trying to cut 25 pounds off.
Hey Ben. Thanks so much for this wealth of knowledge, it has been a great resource. I am about to start my first peptide cycle (Mod GRF and Ipamorelin) but I was wondering about using a pre-workout that I have come to like that contains RAD-140 and LGD. Should I discontinue using this during the cycle or is it safe to still use? Thanks in advance, really appreciate all the info and insight you share.
Hi Ben, are semax and selank nasal sprays as affective as the injectables? Do you recommend regular or the N-Acetyl versions?
Thanks!
Hey quick question you said IGF-1 LR3 becomes somewhat ineffective after30 days because your body becomes use to it. If I plan a 12 week cycle of ghrp2 as you mentioned how do I balance it out since I will not be using the igflr3 for the duration of the cycle
Do you sell a 6mg/1.5mg per vial of TESAMORELIN & IPAMORELIN?
Hello Ben! Thank you for this article. I have a question about the the amount. After doing the math for me, it looks like if I took 100 mcgs 3x per day of each, that would be .3 ml per day. Which means a 5mg vial of IPA will last 16.6 days, and a 2 mg vial of MOD will only last 6.6 days. With this math I would actually need more then 3-4 bottles per peptide. It looks like IPA comes out to 5 vials ( 5×16.6=83) and MOD comes out to 12 vials ( 12×6.6 = 79.2). So I either am confused about how this works, I am getting the math or something else wrong, or your recommendation of vials is slightly inaccurate. I would appreciate any clarification on this as I am interested in the benefits but I want to make sure I’ve got everything down right. Thank you!
William, I use this stack as well…you’re using way too much which can kill you. I’m 6’0” 265lbs and I use 1/3 of what you use. You really don’t want to exceed 100mcgs per day of IGF1-R3 unless you’re lifting and exercising like a professional athlete. 100mcgs is 10 days per vial. 6 vials will suffice for a 60 day cycle.
@trainwithvivek he is genius ask him he can help
I have forgotten the dose for bacteriostatic water in a vial that contains a mix of IPA, and CJC-1295 no dac 4 MG total ( 2mg each). Thank you so much for your time and knowledge
Hey Ben – every heard of Tesamorelin? My doc recommended it as a growth hormone related peptide.
hey ben
i have ghrp-6 5 mg ipamorelin 2mg cjc1295with dac how to use this
Thanks for all the great details. Just want to verify correct usage. Would like to inject intramuscular 1 time a day the following:
Ipamorelin 150mcg Daily 12 weeks on 8 off
IGF-1 LR3 100mcg Daily 12 weeks on 8 off
Mod GRF 1-29 100mcg Daily year round
Does this make sense for 53 year old, 6’4” 235 lbs. 5 days workout. Weekends rest.
Unfortunately, I can't give advice on this sort of thing without knowing way more about you and your health. I'd be happy to help you out with this via a one-on-one consult. Just go to: https://bengreenfieldfitness.com/coaching
Ben, is it safe to take CJC-ipamorelin and traditional HGH at the same time?
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Hi Ben, I’m looking to do the IPA and MOD GRF. Do you have to still mix the MOD with bacterial static water like you do with the ipa?
Also, would it be wise to take oestrogen blockers while I’m on this cycle?
Thanks
I’m interested in a simple stack, length period and protocol of CJC and IPAM. (Don’t know if I should use DAC or not)
From my understanding:
CJC NO DAC
200-300mcg Split dose, 2-3x a day, before food
IPAM at the same?
On 5 off 2 for 12 weeks?
Ben, can you stack Sermorelin and Ipamorelin together? If so, what dosing would you recommend?
to all.. Is it a good idea, once all 3 compounds are mixed, to transfer 2 into the 1 remaining? so all 3 are in 1 vial ? it would be more convenient to pin just 1 time before bed and be done.. i already do 250iu hcg, then draw 75mg into same 29G insulin needle.. and inject Subq.. every 4 days… simplicity is key for me.
I mean CJC-DAC
Why is there such a lack of information for women on these items? In my opinion, if women knew the benefits they could reap from a few quick additions or modifications to their lifestyle, they would flock to it like many do Botox. However, I have a question. My lab rat is taking .3 mg Somatropin for adult onset GHD. Recently, I ordered the little one some HGH frag (175-191) and Ipamorelin. Can little ratty take these combined and still be safe?
Use the HGH frag 176-191 with Mod Grf 1-29
Hi Ben, thanks for the really informative write up… just your thoughts about Ipamorelin. Do you know if Ipamorelin Acetate can be injected directly or requires purification?
I wanted to buy a blend of CJC 1295 NO DAC 5MG with GHRP-2 5MG. Can someone help me with the dosing, since both peptides come in the same vial? Any help is appreciated.
Dilute it with 5ml bactériostatique water
Inject 10-15 Units in the morning, and before you sleep
That amounts to 1mg/ml or 0.1 mg – 0.15 mg a dose (of each)
Any thoughts of why Ipamorelin + cjc 1295 no Dac would cause sleep issues? Most people experienced better sleep. Thanks!
Are you getting hot flashes too? It means it’s working but the increased GH would cause temporary stimulation at least for me. Dies down after an hour. I usually pop a benadryl to put myself to sleep…
Hi Ben,
Check this site SEXstore.ie
Sir I’m a wrestler my ambition is Olympics . I want become no 1 Wretler in world . What should I use . How much months do I need . What should I stack . Please recommend a good cycle please
I can definitely help you out with via one on one coaching. Go to BenGreenfieldFitness.com/coaching for more info.
Hey Ben,
I have recently purchased GHRP-2 and Sermorelin (Was meant to be Mod grf 1-29 but the order mixed up) which I intend to stack.
I am going to mix the two together at an appropriate concentration and administer via nasal spray so as to avoid 3 pins a day.
Do you think this method will work? (I have 10 bottles of each by the way, so the lessened effectiveness of the nasal spray shouldn’t be a major issue).
I’m doing a fast for several days and was wondering if it would be best to continue or discontinue use during this time.
Thanks
“The average dose of Ipamorelin is 200-300mcg, taken at two to three times per day.”
I want to clarify, this mean 200-300mg total per day, or 400-900mg total per day?
Thank you!
Dose 100mcg per shot (saturation dose) 2 to 3 times a day on an empty stomach, 30 mins before food.
Ben,
Looking for dosage and time for 1 pinning per day for IMP/MOD/IGF stack. What would your best suggestion be? AM or before bed? All in one pin?
Thanks
Hi Ben, whilst the stacking does sound very appealing, can you confirm on what it is that is being injected exactly…ie are these man made chemicals? If so, whilst I appreciate these peptides are sold for research only, do you know if there are any future implications?
Hi Ben,
What do you think, does it make sense to add HGH Frag 176-191 to this stack if my goal is the rapid fat loss?
I am not a doctor and this is not to be taken, interpreted or construed as medical advice. Please talk with a licensed medical professional about this.
Ben, do you know if it is common for non-diabetic bodybuilders to experience hypoglycemia due to injecting subcutaneous IGF-1?
Of course mate, do a bit research on your own and you will find out when taking igf it is common to go hypoglycemic in a matter of minutes actually…
Drink a can of sprite when you start feeling this way and it helps, from my experience.
If you are using IGF 1 Lr3 then it is normal to see glucose levels drop. Make sure you drink a cup of Orange juice or something that is a carb after this peptide use. Look it up, should have done some research 1st. Be careful !
Ben
My doctor said you don’t need to cycle CJC/Ipamorlien and can take it consistently if you do 5 days on 2 days off. Have you heard of this?
Yes – I have also come accords similar literature, but I’ve also heard 12 week cycles, and the people who said the latter were peptide researchers.
When in doubt… cycle.
Rather than interrupting your cycle every week, resulting in constant peaks & troughs to your GH, it’s safer & more effective to run a consistent cycle, then take a couple of weeks off. This has additional benefits, on top of simply giving your pituitary a break (inc normalisation of IGFBP3).
At normal doses, Ipamorelin causes no pituitary desensitisation, nor other detrimental sides, so it’s safe to use long term. CJC-1295 (or the shorter half life Mod GRF 1-29) has more pronounced effect on the pituitary, so it’s more important to cycle these.
Hi Ben,
Just wondering does consuming collage peptides 10g protein in the peptides before using these gh peptides cause them to work less efficient? Do I need to take them in a fasted state? I read that either fat or protein should be okay as long as insulin doesn’t spike up? not sure which one raises insulin.
Thanks,
Ronald
Protein is more likely to spike your blood glucose… Would probably be best to take without significant source of protein
Need help not sure how to dose. I just received 3 bottles of Ipam and CJC/1295 no DAC how should I start taking these 2 at what dose?
Two options: 3x a time (100mcg of each) – waking, before lunch or 2 hrs after lunch, and before bed.
OR 200 mcg before bed between 6pm and 8pm.
Either way, go 5 days on, and then take 2 days off.
I’m currently on this, and my doctor outlined the above.
What kind of doctor ? General practitioner?
Hey Ben,
Where do you get your peptides now?
I've been using an oral form from DrSeeds.com… It's more convenient and I find it's better for my gut than injections (code: BEN)… If you're looking for an injectable source, I recommend posting this to the Kion Community. It’s a completely free online community of like-minded people who both have advice and are seeking advice. Facebook.com/groups/GetKion/
Dr. Seeds.com body protective complex performance. Is that what your using? If so what are you stacking it with?
I want to be hight please help me
“Ipamorelin: 5mg typically runs about $32. Depending on your frequency of cycling and dosage, that will last you about three to six weeks. So for a full twelve week cycle, get three to four bottles.”
Can you help me understand the math? 5mg would be 5,000 mcg right?. And 5,000 divided by the daily dose of 600mcg, is 8.33 doses. So my math says each bottle will only last 8 days.
What am I missing?
I was wondering the same thing-
According to other sites, the daily dose is 200-300 mcg to be taken in 2-3 100 mcg shots presumably. I believe that is what he failed to clarify here. Therefore at 200mcg per day 1 5000 mcg bottle would last 25 days.
Bingo… Thanks ;)
Where are you guys finding your sources?
Question, how many CC’s of bac water did you delute this will? I’m confused on the delute amt
I recommend posting this to the Kion Community. It’s a completely free online community of like-minded people who both have advice and are seeking advice. Facebook.com/groups/GetKion/
im trying to figure out how many mcg of cjc1295 ipamorelin to take daily, i know they say 300mcg of ipamorelin 2 times a day, but i have a blend of cjc ipamorelin at 5mg each in one vial. im thinking i would take a total of 600mcg 2 times a day for a total of 300 of each
200 to 300 MCG is a DAILY DOSE.
if you are taking it twice a day 100-150 per dose is recommended.
how long do I have to fast before cjc ipamorelin injection? and after injection to eat?
I recommend posting this to the Kion Community. It’s a completely free online community of like-minded people who both have advice and are seeking advice. Facebook.com/groups/GetKion/
Ideally on an empty stomach (or a couple of hours after eating, to let your blood sugar & insulin response settle down).
Wait 30 mins before eating after administration.
Hey Ben, any idea if you can take HGH with hgh-inducing peptides and see combined more positive results?
Like, you could only afford 2ius HGH but wanted to add MOD GRF 1-29 with GHRP6 to get more HGH for the same dollar?
Increasing natural GH while adding synethic is an idea I’m interested in
Nice article, sir
I recommend posting this to the Kion Community. It’s a completely free online community of like-minded people who both have advice and are seeking advice. Facebook.com/groups/GetKion/ … I'm not currently able to use HGH as it's banned by USADA and WADA, but many in the community have experience and might be able to offer a more informed experience.
Everyone says you can’t get real IGF-1 LR3. Is this true? I don’t need to know the source, but does anyone actually sell real IGF-1 LR3
Ok goofy question and I apologize if it seems odd, all the peptides are in separate vials do you blend them or do you take 2-3 shots? Does it keep its effectiveness? I ask as I just started and I am taking a blend of GHRP 2, GHRP 3 and serolim, 20 ccs daily
I was wondering the same..
Hi Leonidas
Reall IGF-1LR3
a little expensive IGF-1 LR3: 22$ /vial, 1mg/vial.
Will you still need it,and The MOQ 20vials.
Conrtact with me if you need it
Web : HTTP://www.classy-peptides.com
What`app:+86 15738130033
My Email: [email protected]
Best regards
Fiona
How long before body fat drops with CjC 1295 with Ipamorelin? Also on injectable testosterone and oral BPC-157. Scale is going up for me. Could that be water weight since I’m only 3 weeks in?
How long do you allow between cycles of IPA & CJC?
Also, my docs are selling the peptides out of their office – $600 for a 12 week cycle. Seems like a lot. The don’t write scripts because they want to sell at a markup. Suggestions?
Hi- same Question as Shelle – my doctor prescribes my ipa/cjc-1295 monthly. It’s around $250/month.
I’m told to inject subcutaneously b4 bed but I actually do it in the morning early. I’m on my 4th month now but since I was not taught to reconstitute properly I kind of discount my first 2 months somewhat! I was told to take 20 mcg once at bedtime / empty stomach for a year. Along with a T pellet (which has helped me a lot btw) & many vitamins. I have lost 15 pounds but now am at a plateau these last 8-10 pounds. I also have carpal tunnel symptoms since I started peptide therapy & was very relieved to see it’s a side effect! Thank You, Ben for this & all the info! And to Shelle, I’m right there with you, sister! $$$$$ !
I don’t see many remarks from women on here. I take mine in the morning as well When I take it at night, it gives me a bad taste in my month. I fall asleep but wake up shortly after I fall asleep and can’t go back to sleep, so I switched to morning. I’m wondering if I should take if earlier. Do I not reap some of the benefits by taking it in the morning instead of at night. Do you take if as soon as you get up? Have you found any outside information on women and peptides?
I am currently on Testosterone replace therapy for low “T” (.5cc weekly).. Can I stack Mod GRF 1-29 along with Testosterone?
I would check with your doctor about this!
Yes, you can.
Hi Ben,
Loved this episode. I’m leaving for Everest on April 7 and plan to use Kion bars and Jay’s Alti-Fuel product to help me perform well at altitude. Could you please ask Jay for his thoughts on dosage of his product on Everest? Thanks!
I’m looking for MOD-GRF 1-29 and I’m finding CJC-1295 NO DAC. Newer version, different structure?
Different name but same thing.
Hi Ben,
Really great article. Having read through I just wondered two things.
1. Does the IGF have to be injected intramuscular and can it be done subcutaneously?
2. Do you dilute the IGF with Bac water as per the hex and Mod G? Or use something else?
Yes to Subcutaneous. And yes, when you get it, it needs to be reconstituted.
Confused on timing. I have ipam/modgrf as well as lgf1-lr3 …. Understand the ipam/modgrf needs to be on an empty stomach .. No food for an hour or so prior and stay fasted for 30 mins after injection… But LR3 needs to be taken with food? Trying to get the most effective dosing… Was going to do ipam/mod 1st thing in morning prior to fasred cardio… Then LR3 with my meal … Or pre workout w a shake and ipam/mod again at bed if stomach is empty… If I added LR3 to my bedtime injection… Is it still effective do food?
Any recommendations on where to buy these research peptides? Blue Sky Peptide was completely bunk. I won’t know for a week or so about peptidesus.com, but I’m not holding my breath. There used to be a solid supplier on the dark web, but since these are legal for research purposes I hate to go through so much effort.
There seem to be thousands of sites all claiming to be legit, but I’d be surprised if 10% sold what they claimed they are selling.
I've been using an oral form of BPC from DrSeeds.com (Code: BEN saves 15%) that has been awesome… otherwise, this would be a great question to post to the Kion Community, as the issue with sourcing has come up more than once: Facebook.com/groups/GetKion/
Peptidesciences.com or peptidepros.net have both proven reliable quality in my experiences with them.
Peptidesciences.com is my source.
Bumping old thread, any updates on sources?
Have tried some of the recommended here but CJC/Ipa does not produce a flush after injection (had this effect on prior cycles when I tried, but source went bunk).
Can someone PM or recommend please,
Did you ever frequent the Datbtrue forum? You’d have loved it there. Quick question, you said “You can take Ipamorelin for twelve week cycles before it becomes ineffective” got a link to the study that’s from? I was under the impression Ipamorelin actually improved local pituitary signalling?
Hi Ben,
Great article indeed, lots of knowledge, thanks for sharing. I would like to share with you my experience and results. I am currently taking HGH Humatrope (Somatropin) 3iu daily in the mornings. 1.5iu as I wake up 6:20 am and 1.5iu 8:30 am just as I finish my CrossFit Misfit program WOD’s. I am 45 years of age. Workout since 18 years old, take care of what I eat and try to eat clean. I have been doing intermittent fasting 18:6 for 2 years 100% consistent. I am 6’2 and started weighing 194 lbs before doing HGH 3iu that was 2 months ago and now weighing 180 lbs. After doing HGH 3iu exactly 60 days ago I have shedded 14 lbs of fat and going for more fat loss. I feel GREAT..!!! I am just a bit confuse with IGF, IGF-LR3, GHRP-2, GHRP-6, GHRH… Shoudl I need to add one of this aminos to my Humatrope 3iu daily shot I take? I have read a lot and just want to be on the safe side. Can you please give me your thoughts and advice on my HGH I am taking.
Check out this article: https://goo.gl/wwkhF8
Thanks Ben. Will reach out for you. Need some advice. Thanks for sharing.
Im trying to heal a bunch of tendon issues. I haven’t started any thing yet except normal stuff omega,glucosamine MSM,chondroitin recovery drink and diclofenac. I just got mk677 and bpc157 ste they good to stack together? I just got my igf-1 Levels tested yesterday so I can see the results of the mk677. Just wondering if I should be stacking the 2? Thanks for any info.im thinking 20 -25mg of mk677 and 200 through 250mcg of bpc157 a day. Just want to know if it’s good to do together thanks
* * * * * Please feel free to highlight the errors in my post, should you find any. My knowledge is a bit rusty so I welcome all who can offer additional insights, improved accuracy, more relevance, etc. * * * * *
Hi Wesley,
Just my 2-cents here…but this worked wonders for me:
Make several (3 or 4) injections of BPC-157 around the damaged/affected region, as if you were trying to mark out the perimeter of an invisible ‘fence’.
If your desired dosage per injection is 200mcg, for example, and you’d like to make a total of four (4) injections around a degenerating tendon in your elbow; well, obviously, you’ll be making four (4) 50mcg injections around the most vulnerable/susceptible section of said tendon.
Incorporate TB-500 into your healing peptide regime and you’ll be making great strides towards a fully-restored tendon in weeks…not months.
Of course, splashing in some IGF1-LR3, a GHRP-variant and a GHRH-variant will certainly not hurt your recovery; quite the contrary.
A few years ago, I suffered from excruciating paid in my left forearm (Tennis Elbow) as my tendon was degrading at faster rate than it was healing. After 18-months of enduring hell, my right forearm decided to, also, provide me with nothing but agonising grief. After 2-years of using gels, creams, regular stretching, ongoing massage therapy, dry-needling, physiotherapy…the works…I was borderline having a psychotic break, just from the pain that both of my forearms were putting me through; as well as the fact that I could barely do 50% of my gym workouts, on account of my forearms being so weak, they couldn’t even support the weight of my outstretched hands.
Enter: BPC-157, TB-500, IGF1-LR3, GHRP-6 (and later, GHRP-2) and MOD-GRF 1-29.
My family doctor remarked “you’ve undergone 6-months of healing in 6-weeks”…and I had.
That was about 18-24 months ago but I still pump a few hundred mcg of BPC-157 in those two areas about 1-2 times every 6-9 months; I still take about 500-1000mcg of TB-500 per week (sometimes, none at all because I just forget); and I cycle IGF-LR3 and my GHRP/GHRH selections as well, throughout the year.
Not saying you (or anyone else) will experience the same drastic healing process that I enjoyed a few years ago but, with quality products, correct dosing, strict timing, appropriate injection-site selection, etc. combined with a healthy diet, cardio, quality sleep and a heap of L-Glutamine (i.e. 100-125g daily), I honestly can’t see why you (or anyone else) should not be able to enjoy the wave of pain-free relief that comes with such a legitimate healing process.
All the best for your recovery, Wesley.
MK 677 is effectively an oral version of Ipamorelin, so yes it stacks great with BPC 157.
Take a split dose of around 20mg MK 677 daily & inject 200mcg shots of BPC 157 subQ close to the injury site 2 or 3 times a day.
For most issues this will result in healing several times faster than normal.
Amazing article, thank you Ben. Quick question, what are your thoughts on using prescribed hgh in the morning per protocall and peptides at night like ipa and cjc-1295 no dac?
Not Ben, but perfectly fine to do so. A lot of people will use peptides alone, GH alone, or a combination of the two and switch things up from time to time. I tend to use both because as you know quality GH gets expensive.
Hi Ben I am planning to start genotropin 2iu/day for 5-6 months. I would have gone for aforementioned peptides but currently in India it’s hard to find a genuine source.
Okay so my question is do I need to combine genotropin with something for best results(lean physique, antiaging, elevated energy etc) I mean I will be taking all the necessary supplements but is there anything else I should use in an injectable form!!!
THANKYOU SO MUCH IN ADVANCE
MUCH APPRECIATED
Pretty broad question but there is nothing wrong with running GH by itself. There is nothing that people run “alongside it” , if you will.
Hey Ben! I want to take Ipamorelin, I’m a female and I’ve been an athlete my whole life. Any tips on how to get started? I’m on the fence on doasage (200?300?) and morning or before my workout? Thanks for your time!
From my experience morning times are when your GH levels are at peak. I would start off at 200mcg a day. On training days one dose 40 minutes prior to working out, and the last dose before bed. But remember peptides are not for HUMAN CONSUMPTION! ;)
ha ha ha, all peptide sellers make that disclosure. Ignore it?
200 is a good starting point. Best bang for your buck will be if you get Mod-GRF to run alongside of it. GREATLY increases the response from the Ipa. And you ask morning or workout…why not both!? ;) Either is fine. Most probably consider dosing upon waking the optimal choice if only doing one per day, but all I have read there isn’t a huge difference between the two so whatever works best or is easiest.
Is once a day 200mcg dosing sufficient?
Hi Ben.
Can you take Mod grf 100 mcg dose once in the afternoon and not before bed as my partner wouldn’t understand if I did it at home.
You can inject a dose of 100 mcg of Mod GRF about thirty minutes before a meal (when insulin and blood sugar tends to be lowest)
I didn’t pay much attention to this article after seeing it didn’t even mention the main growth hormone, HGH. The spelling and grammar mistakes are just careless, enough to that it I’m suspect of the quality of the information if the author can’t do a simple spell/grammar check that a 12 year old can do.
Think you better read through your comments, people in glass houses shouldn’t throw stones.
Lance – You may want to ask a twelve year to proof read your troll commentary.
Lol
Poor guy…Probably dont feel well inside.
Im gonna stack genotropin and igf1 lr3, Do you have any clue what dosage?
Thanks.
Norwegian dude working out in cancun, Mexico. Life!
“…enough to that it I’m…”
Wow, dude. No words.
Best place I have bought peptides is comocompounding.com.au really great service and send internationally I don’t live in Australia and normally get my stuff within five days packed with ice etc.
In my opinion, these peptides mentioned are the future of healthy sustainable gains and need to be more normalised and not scaremongered. GHRP and GHRH options are by far the cheapest and best way to increase your GH levels.
Thing is though mate youre advising people to buy three or four bottles of igf1-lr3 for a 12 week cycle but in your paragraphs about igf1-lr3 you state dont take it for longer than four weeks. Whats the deal?
Also theres another couple of intracacies in your article which raise one eyebrow.
Fyi im a fan and support your work and what youre doing to yourself in the name of longevity
Igf1 lr3 is to be taken 40 days on 40 day off continuously . Been my proto for 6 months love it . I stack with hgh and tb500 my pumps are awesome . Recovery is unbelievable when running all 3 at once .
Hey Ben I am a Triathlete, super confused (Aicar.. Gw1516.. SR9009.. EPO.. IGF.. etc !! ) about what shall I take ! can you tell me best things to take that would possibly stack together ! thanks man !
How do u feel about me mk677 for a ghrh
Hi Ben,
Great info here I’m new to the peptides started with Sarms few months back I liked what the results were so I moved up to hgh going on 2 months just started to benefit from the fat burning so I decided to add IGF1-lr3 after 2 weeks of using it my pumps are incredible and I feel great. My question is the IGF1-lr3 came to me in a liquid form I am injecting into my shoulders but noticing that the areas I pinned myself are sore still and a bit hard from 2 weeks ago any idea what could be going on?
Where did you find decent igf-lr3
Am running 2 iu x2 a day and was wondering if lgf-lr3 would do anything
When do I start taking the pcts with the stack.
When do I start taking the pats with the stack
Hi, I am beginning to take CJC1295 no DAC with Ipamorelin (2000/2000). I am taking 100mcg morning, 100mcg post workout and 50mcg before bed.
I will add IGF1-Lr3 at 20mcg/day
What do you think about those mixes?
goals: losing fat and building muscle
Edith. thanks :-)
Not a bad mix, but be sure to cycle off. I'd be happy to help you via a personal one-on-one consult. Just go to https://bengreenfieldfitness.com/coaching. and then choose a 20, 30 or 60 minute consult, whichever you'd prefer. I can schedule ASAP after you get that.
Hey Ben, love this article
I have been carefully peering through your writings on how to use these peds carefully and have a simple question
Is it unwise to stack the peptides in this article with bpc157 and/or tb500?
And also is this something you would run with Cardarine and Ligandrol?
Thanks for all the work that you do
You can stack with either BPC, TB or both with no crossover but I would be careful running these with SARMs as you don't too much GH.
DO NOT STACK TB500 WITH IGF1 !
This will drop your blood sugar instantly and cause possible issues including loss of consciousness. This isn’t a joke
Minimum of 24 hours between these two different shots.
Hi Ben, loving your article ref the peptide stack. Would you get the same effect if you took a 30 day course of Metatropin GH at say 6 IU per day as apposed to a 30 day course of IGF, ipamorelin and GRF1-29 (dosage as per article)?
I will look forward to your response
Hi, my boyfriend has been taking peptide stacks for a while now and I’ve watched the improvements so I’m ready to start. However, he is suggesting i start with only the ipamorelin & GRF 1-29. He says it’s not a good idea to mess with my insulin. We are both healthy adults, who spend a lot of time in the gym and I’m pushing 40 years old and really seeing the signs of aging -everything I just read in your article indicates i’m missing the most important part, the GH or IGF-1. Would you recommend taking just the ipamorelin & GRF without an IGF??? Please help.
Hi there, I'm not a doctor and don't know anything about your current health status/medical history so unfortunately I can't advise on this beyond what's in the article. A great place to get advice for this sort of thing is the Kion Community. Facebook.com/groups/GetKion
Hey Ben, you mentioned that CSC-1295 w/DAC impacts the pituitary gland after 4/5 weeks.. Could you share the research to support this, as I have been unable to find any negative research; hence, I was just about to start a course of it, due to the fact I can inject every 4 days.
Start here: https://www.ncbi.nlm.nih.gov/pubmed/16352683 – that kind of GH pulse can be hard on the pituitary long term.
Hey Ben – Big fan, thanks for all that you do.
Do you have any recommendations of where to purchase peptides online? Anti-aging clinics mark up the product significantly but want to ensure we are getting product from a reputable lab when purchasing online. Any suggestions. Thanks
Yes, all recommendations are linked in the article above.
Thanks Ben, but Proven Peptides do not have any of the 3 compounds you reference in the stack. Any alternative sites or product from Proven Peptides?
Hi Ben. I am having a hard time finding the recommended peptide vendors. Will you please post a link?
I already have dr prescribed Ipamorelin/CJC so all I need is the IGF1 LR3
Please let me know and thank you for the article!
Hi Ben i have a quick question regarding peptides. Having read your page on the best combination of three peptides to take as a stack, is it ok to mix the peptides in the same syringe to avoid multiple injections? Or should they be kept completely separate?
I am not a doctor and this is not to be taken, interpreted or construed as medical advice. Please talk with a licensed medical professional about this. I have not found any data to suggest they shouldn’t be mixed in the same syringe; however, given the ease and their complexity I opt to separate each specific compound to its own syringe. These are just my own personal thoughts and not a prescription or a diagnosis or any form of health care whatsoever.
Just FYI…currently using doctor provided peptides, doc advised me that mixing in same syringe can lead to unintended/unwanted pharmaceutical effects given the fragility of the peptide bonds.
Ben,
What do you think of stacking Sermorelin and Ipamorelin and/or just taking CJC.
Mo and Ben,
I too am interested in one’s thoughts on stacking Sermorelin and Ipamorelin given that the former is known for arguably being safest GHRH & the latter for being one of the safest GHRP as you discussed in article.
I hope to hear a response and would be very grateful!
Hey Ben, Ive been trying to find information on doing peptides and sarms at same time. For example I have ghrp-2, lgd, and ostarine on hand. Would the 3 of these make for a good stack or should i do something else with the ghrp? Thanks in advance
Hey Ben, was doing some extra research and had a quick question regarding the IGF-1 LR3 component in this stack…
Since LR3 is said to have a 20-30hr half life, would that affect the efficacy of the other 2 peptides?
(Since they’re intended to increase GH and therefore IGF, if LR3 is circulating in your body all day, wouldn’t that cause your body to not convert the other 2 peptides to GH>IGF?)
I am not a doctor and this is not to be taken, interpreted or construed as medical advice. Please talk with a licensed medical professional about this. I don't see why your body would pick and choose which to uptake so I think they’d all be advantageous.
Is it safe to pair this stack with SARMS GW-501516, SR9009, & LGD4033? Would dosages stay the same?
Yes it is – this is a popular stack and the aforementioned dosages remain consistent.
Hi Ben! Greetings from Finland😊 I found your site and it’s pure awesomeness!
I have some cjc with dac and you did not recommend that. What would be the safest way to use it? I wouldn’t like to throw it away. I do apologize my bad English-skills!
This is a perfect Q to call into the podcast! Record your Q here: bengreenfieldfitness.com/ask-a-podcast-question/
Hi Ben,
Thanks for the great info on the stack and the peptides.
I’ve been dealing with debilitating fatigue for over 10 years now and was just diagnosed with Idiopathic Hypersomnia. One of the remarkable findings during the sleep study was a complete lack of NREM-3 sleep (Delta wave sleep). From what I understand Growth Hormone is released during Delta wave sleep so I’m interested in taking the Mod GRF 1-29 to help release growth hormone right before bed.
Do you have any sense on if a GHRH will help induce Delta wave sleep? And/or do you know any additional tools that might help induce Delta wave sleep naturally (thus improving Growth Hormone release)?
Thanks for your help!
I would check out this article I wrote that features a product that can help induce delta sleep. https://bengreenfieldfitness.com/article/sleep-ar… You can also do a search on BenGreenfieldFitness.com to find more info on delta sleep. This is also a great question for the Kion community! Because I get so many questions like this and it's impossible for me to respond to everyone individually, I built this community of like-minded people who both have advice and are seeking advice! Facebook.com/groups/getkion/
Can you run Ipamorelin and CJC No Dac at 100mcg every night indefinitely without causing desensitization? Also when looking into the legitimacy of peptide sites what kind of reports should I ask of them besides an HPLC report?
Best,
Noah
You still need to cycle, as I explain how to do above in the article. You can't go indefinitely. Also, a lab chromotography will usually suffice. I will certainly vouch for the sources in the article above!
My doctor recommends 5 nights on and 2 nights off, pretty much indefinitely.
I really would like to order some Peptides and was hoping to get your input . If you could either recommend another site or confirm that peptide warehouse is good legit site to order from ; that would be great and very much appreciated .
i am very happy I found your site and have learned quite a lot listening and reading to you and your guests . I have been trying to find a legit source to order from . You have recommended a few places and knowing that your name and reputation is also at stake by doing this, is peptide warehouse a site you still recommend ?
Thank you
Hi Do you have an updated coupon code for peptide warehouse? The one you have listed is expired. Thanks!
Been a while since this article was written. Any updates? And do you still recommend Peptides Warehouse and PremierPeptide.com? (Coupon code expired on PW.)
Check out: https://bengreenfieldfitness.com/transcripts/tran…
ya sure that’s the right one? I don’t see anything on this topic in that podcast transcript.
dont use peptide warehouse, they havent filled my order and its been 3 months, ive called, emailed, and nothing, they taken my money though. dont use them. terrible.
And for others that have had their orders filled each time and no problems? Have you tried their products? If you did not receive shipment, how do you know they are terrible? Problem with your order doesn’t have any influence on product quality. This site has recommended them. State your source if not PW.
I heard about healing peptides. Will I get the healing benefits with this stacking, or should I add a bpc 157 to this stack?
Hello Ben, thanks for your great article.
When you say ‘You can take Ipamorelin for twelve week cycles before it becomes ineffective or the risks for side effects increase.’ can you tell me how much of a break is recommended between cycles. Would 2 weeks off be sufficient before starting again?
I would generally recommend a longer period around 4-6 weeks to allow the receptors in the body to clear.
Hey there! Thank you for the killer article. A lot of great information!
I have a quick question for you. I am 5’2 female at 112 lbs. I want to use ipamorelin and sermorelin together. Is that safe to do? Is it necessary? And if so how would you suggest I stack them?
Thank you so much!
Hey Alyssa, I am not a doctor and this is not to be taken, interpreted or construed as medical advice. Please talk with a licensed medical professional about this. These are just my own personal thoughts and not a prescription or a diagnosis or any form of health care whatsoever. However, I don't see a need to take both. If you do stack them, then try to follow my instructions above, although for precise, customized dosing I'd be happy to help you via a personal one-on-one consult. Just go to https://bengreenfieldfitness.com/coaching. and then choose a 20 or 60 minute consult, whichever you'd prefer. I can schedule ASAP after you get that.
Hi Ben,
Great informative article. Was wondering if you had any idea about the half-lives of the components of this stack and how long they would be detectable. Also would they be detectable in urine or just in blood?
Love the site, thanks for your time.
It's a really short half-life… Like less than a day. But during that time it would be detectable in both urine and blood.
Hi Ben,
I have been reading your articles and find them to be very insightful. My name is Rod, and I’m a fit 50-year-old guy that knows his way around a gym. I’m 6’5” and when I’m at peak fitness I weigh in at around 122kgs. I’m currently weighing 134kgs, after a major job/lifestyle change, disrupting my usual routine.
Anyway, enough excuses. Although I don’t look over weight due to being a big heavy set guy, I would like to achieve my dream physique. I have never wanted to be huge with massive arms and legs, I’m already a big guy, although I would like my triceps and biceps to have a little more size and definition, my ultimate body shape is more the toned underpants model physique. In my younger years, I knew how to achieve that through diet and exercise, but with age that effort doesn’t seem to be paying off like it once did.
I would like to move some stubborn fat of my belly and lower stomach generally lean up while gaining definition and of course the few small gain tweaks for my arms and chest etc. Three months ago, I started a three-day full body spilt, with a focus on higher rep’s and better/strict technique. I can feel this approach is working, and I’m defiantly get fit and dropping weight but……
For the past 4 months, I have been injecting 2iu’s of somatropin (Dr prescribed) at around 8am six days a week. Although it is quite expensive I must say that I do feel better and I can see a positive result, a slow positive result.
So, my question; would there be any benefit to me taking my morning injection of somatropin and in the evening taking an injection of GH, GHRH, GHRP – Peptides (only the two injections each day) …? Or would this just be a waste of money…? Would the money be better spent on a higher dose of hgh….? Or do you have a better suggestion.
I know this question may seem lame to many, but I’m not a full committed bodybuilder, I’m just a bloke trying to look my best, and to achieve this end goal, and I do need the help of hormone, etc. And of course, I want to do it in a safe way.
Can you please help me…?
Best Regards
Rodney
Hey Rod, for something like this I usually suggest you book a consult as I'd need to go into a lot more detail with you. You can do this by going to <a href="https://greenfieldfitnesssystems.com/ben” target=”_blank”>www.greenfieldfitnesssystems.com/ben and choosing 20 or 60 minutes and we'll get you scheduled to go into detail. Hope that helps!
Ben if you are following a carb backloading protocol and the goal is to maximize muscle growth without adding fat, would it be best to take LGF post workout with the high insulin spike. Would it be better to get take LGF pre-workout?
I actually recommend in the morning on an empty stomach…
For “the stack,” you mentioned that no more than 4 weeks for the IGF as it can have side effects, but then suggest a 12 week cycle overall. The remaining items of the stack you didn’t indicate anything that would prohibit a 12 weeks cycle. My question is how do you suggest integrating the IGF in to the cycle? For weeks 1 to 4 all 3 (IGF/lpalmorelin/mod) then weeks 5 to 8 (lpalmorelin/mod), and then 9 to 12 weeks (IGF/lpalmorelin/mod)???
Also, for folks who travel for work, any suggestions on staying consistent with your cycles?
Great article! I learned a lot and am researching and learning.
I am not a doctor and this is not to be taken, interpreted or construed as medical advice. Please talk with a licensed medical professional about this. These are just my own personal thoughts and not a prescription or a diagnosis or any form of health care whatsoever. Basically, you can use IGF the whole 12 weeks if combined with these others.
Few questions here Ben:
-Why is a 12 week cycle of IGF allowable so long as these other two compounds are administered in tandem?
-Can I expect GH stomach from running a mild to moderate cycle of what you’ve put forward here (IGF, ipamorelin, mod GRF)?
-Are there any negative short or long term sides i should be aware of? will my pituitary recover to its prior facility once i’m done with my cycle?
Hi Ben – Just want to confirm the dosing. So e.g., for IGF1, if my dosing is 100 mcg, then each vial of 1 mg will contain 10 doses. If I reconstitute with 3 ml in total, then each injection will be 30 units on the syringe or a little under 1/3ml.
If this is true is seems that each vial will last for less than your estimate above for each of the peptides — just want to make sure I wasn’t over dosing myself. Thanks
Yep, your math is accurate, but make sure you check on peptides calculator I link to in article to make 100% sure! A vial typically has more than 1mg FYI.
Taking just ipamorelin 300mg/day split to 3x (100mg/shot) for 12 weeks will that give enough result to grow lean mass muscle .. I am already fit by the way just plan to grow more lean mass , 171cm height , 65kg , 9.5% body fats
Hey Ben, have you monitored your Delta sleep using this stack? I’ve got an Oura ring too and am having difficulty getting my percentage up to 15-20% as you wrote in your sleep article. Any suggesting (or articles) on increasing Delta? Thanks for applying your keen mind to all this!
Definitely look into this: https://bengreenfieldfitness.com/2016/02/how-to-u…
Can you give an explanation of this stack vs. real HGH, and why you chose these peptides over exogenous HGH?
Real HGH also are not legalized by the FDA, so you have to obtain a prescription of the hormone from a doctor, but you can still buy online. Problem is it is far more likely to shut down pituitary production than these stacks.
Hello, are you familiar with growth hormone releasing peptides that can be administered as a cream rather than an injection? These are very popular in Australia but I question whether they are actually absorbed!
Dosage with creams can be very tricky. As can the scary part about being careful not to get it on loved ones, bedding, etc…be careful.
Hey Ben, I too would also be interested in your thoughts on sermorelin. As from what I’ve read it’s similar to ipamorelin (sermorelin supposedly being the “safest” GHRH) I was looking into stacking sermorelin & ipamorelin, but I had read a few places that you can dose for 6 months?
I don't see any advantage of that over taking ipamorelin by itself, but I did NOT research sermorelin for this article. Likely very similar but again, haven't researched it…yet! I do know they both have a number of similar effects on animal test subjects….and sermorelin makes you sleepier.
What’s the best sarm/peptide combo for shedding fat and maintaining muscle? Or can you take one?
Assuming that you are not competing in a world anti-doping associated sanctioned sport, the one that I wrote about in this article is best. But I can always customize something for you. Here's how: go to <a href="https://greenfieldfitnesssystems.com/ben” target=”_blank”>www.greenfieldfitnesssystems.com/ben and choose 20 or 60 minutes and we'll get you scheduled.
CAN ALL GO INTO 1 NEEDLE ? WHAT DO YOU THINK OF BLUE SKY
I prefer peptide warehouse. And yes as I mentioned in the article above you can put this all into one needle.
Hey sorry i must be missing something Ben I don’t see nothing about mk 677 in that article I just see talk about GW-501516, sr9009 and LGD4034, am I missing something Ben?
Oops, sorry, don't know why I thought I wrote about it there…it is also known as Nutrobal and could be compared to peptides like GHRP-6 or Ipamorelin I discuss here, only it doesn't require any injections nor does it have any side effects like GHRP-6. You can take it orally. But not as efficacious as GH's IMO.
You wrote about cycling off of Ipamorelin and IGF-1 LR3. How long should the “off cycle” be?
Great articl,
Thanks
Off cycles are usually 1:1 ratio (e.g. 12 weeks on/12 weeks off)
Hi Ben,
I am confused about how someone would use these in terms of cycles, etc. I am 40 years old and in pretty good shape. I got great results with BPC-157 and TB 500. Is this the they of thing where we do a cycle here or there for a boost, or if it is supposed to be done long term? I can’t believe it is additive and every time you do a cycle you get better with no side effects. I can’t tell for example what a 5-20 year plan would be for something like this. That might be extreme, but if you were thinking longer term, aka 5 – 10 years, how would you do it? I don’t want to F anything up!
Thanks, love your notes!!!!
I've been using DrSeeds BPC capsule for more regular support, then I do a monthly injection. When I'm injured I'll use a more vigorous protocol, but yes there is probably a point of diminishing returns.
Hey I don’t see anything about mk 677 in the article 3 safe Alternatives for Muscle building!
I already wrote about it here: https://bengreenfieldfitness.com/2016/08/safe-alt…
Any thoughts on a high quality, humane elk/deer antler? Thx!
I am a familiar, but it is a night and day difference between a synthetic injection like this and deer antler velvet.
Is this only for men?
No. There are plenty of women that use this.
Great article. Good solid info. In your opinion do you think this will help sore joints
I would say that a better choice for something like a sore joints would be this: https://bengreenfieldfitness.com/2016/05/how-to-u…
Hey Ben do u have any research on mk 677(Ibutamoren) and it’s ability to raise growth hormones? Or any feedback on mk 677?
Yes, check this out: https://bengreenfieldfitness.com/2016/08/safe-alt…
Hi Ben,
I’m 75 and currently the No.1 age group competitor in US in Kettlebell Sport. After coming back from a World Comp in Ireland last November I couldn’t get my mojo back. My age management doctor recommended Semorelin daily injections which I have been on for 3 months. Recommended dose daily for 6 months and then onto a maintenance schedule. I am feeling better, sleeping better, lost some fat, and have more energy. This past weekend, I snatched a 16kg bell 97 times in 5 minutes with one hand switch. I’m training for a world comp in CA in February 2017. Your thoughts or comments on Semorelin.
That is one that I have not yet tried or researched, but perhaps someone else here in the comments section has…
You forgot talking about the ”sarm” mk-677 (ibutamoren) wich is a gh secretagogue, and in my opinion superior to injectable peptides because it’s oral, don’t cause desensitization and has been shown in sutides that it can be run for long periods of time (year plus) without side effects.
I have actually written about that here: https://bengreenfieldfitness.com/2016/08/safe-alt…