-Dr. Adeel Khan…06:35

• How Adeel became the go-to guy in the stem cell  industry
  • Trained by experts in the field like Dr. Galea, the pioneer of PRP
  • Went on to work with Dr. Ian White at the University of Toronto 
    • How to enhance stem cell function 
    • How to better select the best candidates for stem cell therapy
• The key difference between what Adeel and Dr. Ian White and what everybody else is doing is actually having third-party testing to validate cytokine profiles
  • A proprietary process on how to harvest umbilical cord stem cells and amniotic fluid
• Working with a scientist from Italy, Dr. Giuseppe Mucci, founder of the Bioscience Institute

-Profiling stem cells…13:27

• It's called Flow Cytometry
• Profiling stem cells – two important aspects:
  • Quality control – 50% of the money we spend on just stem cell processing is for quality control to test for infections, diseases, and to make sure they're good quality cells
  • Flow cytometry – test to look at the actual markers, called CD markers
• Most clinics offering stem cells are actually offering what are called committed progenitor cells or medicinal signaling cells
• Unless you isolate the actual mesenchymal stem cells or stromal cells and expand them in a facility, they are not true stem cells
  • Paracrine – signaling system that sends signals to reduce inflammation
• Any sort of true stem cells where you're isolating, expanding, or taking perinatal tissue like amniotic or umbilical cord stem cells are classified as a drug
  • Not allowed to be used in the U.S.
• Podcast with Dr. Harry Adelson:
  • The Future Of Stem Cell Therapy, Making Fancy Stem Cell Protocols Affordable To More People Than The Elite Rich, Stem Cell Injection Secrets & Much More With Dr. Harry Adelson.
• Judge Rules in Favor of Stem Cell Clinic
• Expanded stem cells are approved pretty much everywhere except Canada and the U.S.

-Stem cells vs. progenitor cells…18:39

• Progenitor cells don’t engraft and renew tissue; they help reduce inflammation, which is especially important for osteoarthritis
• The regenerative medicine triad:
  • Stem cells – expanded cells
  • Growth factors – expanded cells have growth factor
  • Scaffold – a biodegradable hydrogel made up of hyaluronic acid
• FDA-approved clinical trial for 3D bio-printing scaffold
  • A method to avoid knee and hip replacements
• Using your own stem cells (autologous) vs. someone else’s (allogeneic)
  • Allogeneic is better
• Expanded stem cells have much better results
• Interosseous injections of stem cells
• Ben’s experience with interosseous injections
• It takes 3-4 weeks to expand bone marrow or fat
• Preferable to use the umbilical cord when it comes to IV stem cells
• When it comes to injections, fat is preferable

-Recovery time from the procedure…26:37

• It varies but recovery time is fast
  • Some people are pain-free and feel great in a week
  • Other people have pretty bad pain for 2-3 days and with pain for 2-3 weeks
• It took Ben about five days, and he used
  • Red-light therapy
  • PEMF
  • hyperbaric
• Stacking pathways
• Chronic pain is usually addressed only with pain medication
  • Many things can cause pain
  • Disease starts in the cell
  • Regenerative medicine offers many different therapies and paths
• The Pharmacist docuseries
• Type of IV stem cells used
  • Generally, from umbilical cord tissue, not blood
• Stem cell exhaustion is one of the hallmarks of aging
  • As you get old, stem cells decrease
• Tissue engineering
  • 3D bioprinting
  • Creating scaffolds, synthetic or using biomaterials like hydrogels
• 3D bioprinting
  • We’re not far away from printing organs
  • Instead of getting a kidney donor, you can just print a new kidney and implant it
  • If you had the right type of bio-ink for cartilage, you can print a knee, an elbow, or a joint
• A lot more research is done in China, Japan, and Korea on this than in the U.S.
• China is probably the leader in biomaterials and 3D bioprinting

-What is gene editing?…33:51

• The doctor in China who was arrested because of his work in gene editing
  • Modified the embryo to give it certain traits
• Creates many ethical problems
  • Available only to rich people
  • Creating an elitist society
• Could be used for regenerative medicine
  • The intersection of gene editing, cell therapy, tissue engineering
  • Customizing a cell
• CAR T (Chimeric Antigen Receptor T-Cell) technology approved by the FDA
  • Uses gene editing and cell therapy
  • Edits T-cells to go and kill cancer cells
• First regenerative hospital in the world is being built in Mexico
  • Adeel is going to be the Assistant Managing Director
• Follistatin gene therapy and its downsides
• The peptides used in stacking pathways
  • Thymosin α-1 and Thymosin β-4
  • The thymus gland is one of the master regulators of the immune system, where T cells are created
  • Helps to immunomodulate or to regulate the immune system
• Combination of therapies to be offered in Mexico for treating autoimmune conditions
  • IV stem cells
  • Peptides
  • FMT (Fecal Microbial Transplant) 
• Combining stem cells with exosomes
  • Exosomes – poor man's stem cells; can be good and have their own role
• Effects of stem cells can be more long-lasting than the effects offered by exosomes
• Optimization of hormones
  • Testosterone replacement therapy – frequent injections are most effective
  • Testosterone gels have very variable absorption – some people do not notice any effects at all

-Adeel's daily routine…46:57

• Guided meditation for 10 minutes in the morning
• Taking a DHEA supplement
  • Pumpkin seed oil to combat side-effects
• Intermittent fasting 16-18 hours
• HMB to preserve muscles
• Podcast with Shawn Wells:
  • Fringe Supplement Stacks You’ve Never Heard Of, The Best Nootropic Combinations, The Latest Keto Support Compounds, Supplements That Act Like “Exercise In A Bottle” & Much More With Shawn Wells
• Kion Aminos
• Intermittent fasting risk of losing muscle
• High-intensity strength training
• Bodybuilding
• NAD for sleep deprivation
  • Patches and suppositories
• Podcast with Dr. John Lieurance:
  • The “Dr. Strange” Of Medicine & Biohacking: Methylene Blue, Stem Cells, Lasers, Earth, Air, Water, Fire & More With Dr. John Lieurance.
• Prioritizing sleep
  • Cortisol regulation
  • Red light therapy
• Vitamin C
• Ashwagandha KSM66
• VieLight
• Podcast with Lew Lim:
  • How To Blast The Brain With Energy by Using Red Light Therapy Headsets, Laser/LED Treatment For COVID, Instantly Shift the Brain Into A “Bliss” State & More With Vielight’s Lew Lim.
• DSIP (use code BEN to save 15%)
• Valerian root
• Kion Sleep + CBD + Melatonin

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